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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Macrophage receptor with collagenous structure

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, SRA, HAD, V1a, ACID
Papers on MARCO
Telomere profiles and tumor-associated macrophages with different immune signatures affect prognosis in glioblastoma.
Slatter et al., Dunedin, New Zealand. In Mod Pathol, Feb 2016
Telomerase-positive tumors with macrophages had increased expression of macrophage receptor with collagenous structure (MARCO), CXCL12 and sushi-repeat containing protein x-linked 2 (SRPX2).
[Design and validation of a questionnaire to assess the level of general knowledge on eating disorders in students of Health Sciences].
González Rivas et al., Barcelona, Spain. In Aten Primaria, Jan 2016
Marco community care.
Cover Caption.
In J Food Sci, Dec 2015
December Online Cover: Geometric and temperature distribution models of broccoli florets, from "Heat Transfer during Blanching and Hydrocooling of Broccoli Florets" by Rosalina Iribe-Salazar, José Caro-Corrales, Óscar Hernández-Calderón, Jorge Zazueta-Niebla, Roberto Gutiérrez-Dorado, Marco Carrazco-Escalante, and Yessica Vázquez-López; p. E2774.
The Hand: Shall We Ever Understand How it Works?
Latash, Paraguay. In Motor Control, Apr 2015
The target article is followed by six commentaries written by Alexander Aruin, Kelly Cole, Monica Perez, Robert Sainburg, Marco Sanello, and Wei Zhang.
Microglial Aβ receptors in Alzheimer's disease.
Ye et al., Shanghai, China. In Cell Mol Neurobiol, 2015
The scavenger receptors (SRs) include scavenger receptor A-1 (SCARA-1), MARCO, scavenger receptor B-1 (SCARB-1), CD36 and the receptor for advanced glycation end product (RAGE).
Macrophage Receptor with Collagenous Structure (MARCO) Is Processed by either Macropinocytosis or Endocytosis-Autophagy Pathway.
Kanno et al., Tsukuba, Japan. In Plos One, 2014
The Macrophage Receptor with COllagenous structure (MARCO) protein is a plasma membrane receptor for un-opsonized or environmental particles on phagocytic cells.
Life Sciences in the Ticino: Two Scientists - Two Stories.
Fürst, Renens, Switzerland. In Chimia (aarau), 2014
Luca Varani, PhD, a group leader in Structural Biology at the Institute for Research in Biomedicine, Bellinzona, and Marco Brini, founder and CEO of EnvEve SA, in the Tecnopolo in Manno, describe their life sciences background, their careers and why they percieve their ideal situation being a basic scientist who wants to remain in science, or being an entrepreneur respectively.
Autophagy regulates phagocytosis by modulating the expression of scavenger receptors.
Eissa et al., Houston, United States. In Immunity, 2013
Atg7⁻/⁻ macrophages had increased expression of two class A scavenger receptors: macrophage receptor with collagenous structure (MARCO) and macrophage scavenger receptor 1 (MSR1).
At the (kineto)chore, yeast really are like people.
Swedlow, Dundee, United Kingdom. In Cell, 2013
Now, deploying specialized data processing techniques to achieve super-resolution images, Marco et al.
Microparticles bearing encephalitogenic peptides induce T-cell tolerance and ameliorate experimental autoimmune encephalomyelitis.
Miller et al., Chicago, United States. In Nat Biotechnol, 2012
These beneficial effects require microparticle uptake by marginal zone macrophages expressing the scavenger receptor MARCO and are mediated in part by the activity of regulatory T cells, abortive T-cell activation and T-cell anergy.
Clearance of fetuin-A--containing calciprotein particles is mediated by scavenger receptor-A.
Jahnen-Dechent et al., Aachen, Germany. In Circ Res, 2012
Fetuin-A-containing calciprotein particles facilitate the clearance of mineral debris by macrophages via SR-A.
Surface lipoprotein PpiA of Streptococcus mutans suppresses scavenger receptor MARCO-dependent phagocytosis by macrophages.
Igarashi et al., Tokyo, Japan. In Infect Immun, 2011
These results demonstrate that the S. mutans lipoprotein PpiA contributes to suppression of MARCO-mediated phagocytosis of this bacterium by macrophages.
Soft tissue management for dental implants: what are the most effective techniques? A Cochrane systematic review.
Worthington et al., Göteborg, Sweden. In Eur J Oral Implantol, 2011
If you wish to comment on this review, please send your comments to the Cochrane website or to Marco Esposito.
[The role of the class A scavenger receptors, SR-A and MARCO, in the immune system. Part 2. Contribution to recognition and phagocytosis of pathogens as well as induction of immune response].
Józefowski, Kraków, Poland. In Postepy Hig Med Dosw (online), 2011
Recognition of pathogens by innate immune cells is mediated by pattern recognition receptors (PRR), which include the class A scavenger receptors (SR), SR-A/CD204 and MARCO.
[The role of the class A scavenger receptors, SR-A and MARCO, in the immune system. Part 1. The structure of receptors, their ligand binding repertoires and ability to initiate intracellular signaling].
Józefowski, Kraków, Poland. In Postepy Hig Med Dosw (online), 2011
The class A SR, SR-A/CD204 and MARCO, are characterized by the presence of collagenous and SR cysteine-rich domains in their extracellular portions.
MARCO regulates early inflammatory responses against influenza: a useful macrophage function with adverse outcome.
Kobzik et al., Boston, United States. In Am J Respir Cell Mol Biol, 2011
These results indicate that MARCO suppresses a protective early inflammatory response to influenza, which modulates viral clearance and delays recovery.
The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis.
Brandenburg et al., Aachen, Germany. In J Neuroinflammation, 2010
Data suggest that bacteria induce glial cell activation and rCRAMP expression via FPRL1 and MARCO, and these receptors contribute to the host defence against infection.
Genetic variants in MARCO are associated with the susceptibility to pulmonary tuberculosis in Chinese Han population.
Cao et al., Beijing, China. In Plos One, 2010
genetic variants in MARCO gene were associated with pulmonary tuberculosis susceptibility in Chinese Han population
Inhibition of pulmonary antibacterial defense by interferon-gamma during recovery from influenza infection.
Metzger et al., Albany, United States. In Nat Med, 2008
Direct inoculation of IFN-gamma can mimic influenza infection and downregulate the expression of the class A scavenger receptor MARCO on alveolar macrophages.
CD16 promotes Escherichia coli sepsis through an FcR gamma inhibitory pathway that prevents phagocytosis and facilitates inflammation.
Monteiro et al., Paris, France. In Nat Med, 2007
Decreased PI3K activity inhibits E. coli phagocytosis and increases TNF-alpha production through Toll-like receptor 4. We identified the phagocytic receptor negatively regulated by FcRgamma on macrophages as the class A scavenger receptor MARCO.
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