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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Secretoglobin, family 2A, member 2

Mammaglobin, mammaglobin A, MGB1, SCGB2A2
Top mentioned proteins: CAN, POLYMERASE, erbB-2, HAD, cytokeratin
Papers on Mammaglobin
Detection of human mammaglobin A mRNA in peripheral blood of breast cancer patients before treatment and association with metastasis.
New
Takahashi et al., Ribeirão Preto, Brazil. In J Egypt Natl Canc Inst, Dec 2015
BACKGROUND: Mammaglobin A (MGA), mainly expressed in the breast epithelium, is overexpressed in breast cancer, and has been established as a tumor and promissory marker for the early detection of metastasis.
Mammaglobin as a diagnostic serum marker of complex canine mammary carcinomas.
New
Verma et al., Ludhiāna, India. In Res Vet Sci, Dec 2015
Mammaglobin is a glycoprotein exhibiting homology to uteroglobin gene family.
New methods to improve the safety assessment of cryopreserved ovarian tissue for fertility preservation in breast cancer patients.
New
Pellicer et al., Valencia, Spain. In Fertil Steril, Dec 2015
MAIN OUTCOME MEASURE(S): Expression of GCDFP15, MGB1, SBEM, MUC1, WT-1, and NY-BR-01, selected as markers, assessed by quantitative RT-PCR in samples with confirmed BC metastasis.
Comparative Sensitivities and Specificities of Antibodies to Breast Markers GCDFP-15, Mammaglobin A, and Different Clones of Antibodies to GATA-3: A Study of 338 Tumors Using Whole Sections.
New
Gown et al., Seattle, United States. In Appl Immunohistochem Mol Morphol, Nov 2015
We sought to determine the potential utility of GATA-3 in identifying metastatic breast CA, and to compare its utility with the standard breast markers, GCDFP-15, and mammaglobin A. We identified an archival series of 338 formalin-fixed paraffin-embedded whole-tissue sections of various CAs.
Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs.
New
Robichaud et al., Moncton, Canada. In Mol Carcinog, Aug 2015
UNASSIGNED: Mammaglobin 1 (MGB1), a member of the secretoglobin family, is expressed in mammary epithelial tissues and is overexpressed in most mammary carcinomas.
Sensitivity of neoplastic cells to senescence unveiled under standard cell culture conditions.
New
Rieske et al., Łódź, Poland. In Anticancer Res, May 2015
MATERIALS AND METHODS: Multiplex Ligation-dependent Probe Amplification, TP53 sequencing, real-time polymerase chain reaction (PCR) for MUC1 and SCGB2A2 and immunocytochemistry, together with senescence detection assay and real-time microscopic observations were used to analyze primary neoplastic cells isolated from prostate, breast and colorectal tumors, as well as stable cancer cell lines (MCF7, MDA-MB-468, SW962, SK-MEL28, NCI-H1975 and NCI-H469).
The Novel Marker GATA3 is Significantly More Sensitive Than Traditional Markers Mammaglobin and GCDFP15 for Identifying Breast Cancer in Surgical and Cytology Specimens of Metastatic and Matched Primary Tumors.
New
Beck et al., Boston, United States. In Appl Immunohistochem Mol Morphol, May 2015
UNASSIGNED: Traditional markers mammaglobin and GCDFP15 show good specificity but lack sensitivity and can be difficult to interpret in small tissue samples.
[Immunotherapy for the Prevention and Treatment of Breast Cancer].
Review
Slabý et al., In Klin Onkol, 2014
The assumption is based on the results of several antitumor vaccine trials targeted against HER2, MUC1, CEA and mammaglobin-A, as well as immune checkpoint inhibitors (e.g.
Generation of monoclonal antibodies against MGA and comparison of their application in breast cancer detection by immunohistochemistry.
Feng et al., Beijing, China. In Sci Rep, 2014
Mammaglobin A (MGA) is an organ specific molecular biomarker for metastatic breast cancer diagnosis.
Improved Natural Killer cell activity and retained anti-tumor CD8(+) T cell responses contribute to the induction of a pathological complete response in HER2-positive breast cancer patients undergoing neoadjuvant chemotherapy.
Martorelli et al., Italy. In J Transl Med, 2014
Characterization of anti-tumor T cell responses highlighted sustained levels of CD8(+) T cells specific for survivin and mammaglobin-A throughout NC in patients undergoing a pCR in both arms.
Mammaglobin A: review and clinical utility.
Review
Ceballos et al., In Adv Clin Chem, 2013
Mammaglobin A is a protein that belongs to the secretoglobin superfamily.
Identification of HLA-A24-restricted CD8(+) cytotoxic T-cell epitopes derived from mammaglobin-A, a human breast cancer-associated antigen.
GeneRIF
Mohanakumar et al., Saint Louis, United States. In Hum Immunol, 2012
Data show that HLA-A24-restricted, mammaglobin-A (Mam-A) derived, CD8(+) cytotoxic T lymphocyte (CTL) epitopes that can potentially be employed for Mam-A-based breast cancer vaccine therapy to breast cancer patients with HLA-A24 phenotype.
Detection of mammaglogin A in blood from breast cancer patients, before and after treatment, using a one-tube nested PCR protocol. Association with the absence of tumor estrogen receptors.
GeneRIF
Ghersevich et al., Rosario, Argentina. In Clin Biochem, 2011
MGA detection by the modified nested RT-PCR is a specific marker for circulating tumor cells in patients with breast carcinoma and a negative prognostic factor for the disease
Cytokeratin-19 and mammaglobin gene expression in circulating tumor cells from metastatic breast cancer patients enrolled in North Central Cancer Treatment Group trials, N0234/336/436/437.
GeneRIF
Perez et al., Rochester, United States. In Clin Cancer Res, 2011
A decrease in MGB1+mRNA levels (baseline-week 8) seemed to be associated with clinical response (P = 0.05).
An immunohistochemical panel to differentiate metastatic breast carcinoma to skin from primary sweat gland carcinomas with a review of the literature.
Review
Dabbs et al., Pittsburgh, United States. In Arch Pathol Lab Med, 2011
OBJECTIVE: To devise a panel of IHC stains to distinguish CMBC from SGC. DESIGN: Twelve cases of ductal CMBCs (11 not otherwise specified type, and 1 basal phenotype), 11 cases of SGCs (5 eccrine carcinomas, 3 porocarcinomas, and 3 microcystic adnexal carcinomas), 2 benign sweat gland neoplasm cases, and 2 primary breast cancer cases were retrieved and analyzed with the following IHC panel: mammaglobin, gross cystic disease fluid protein (GCDFP) 15, p63, basal cytokeratins (CK5, CK14, and CK17), androgen receptor, and PAX5.
VivoTag-S 680-anti-human mammaglobin-A monoclonal antibody
Review
Leung, Bethesda, United States. In Unknown Journal, 2011
Mammaglobin-A gene (SCGB2A2) encodes a 10.5-kDa glycoprotein that is exclusively expressed in normal breast tissue.
Expression of human mammaglobin and clinicopathologic correlations in breast cancer: the findings in Malaysia.
GeneRIF
Alias et al., Kuala Lumpur, Malaysia. In Indian J Pathol Microbiol, 2011
The expression of hMAG was found to be increased with breast cancer grade.
Cloning expression, monoclonal antibody preparation and serologic study of mammaglobin in breast cancer.
GeneRIF
Zeng et al., Beijing, China. In Neoplasma, 2010
High serum mammaglobin is associated with breast cancer.
Significance, detection and markers of disseminated breast cancer cells.
Review
Lacroix, Brussels, Belgium. In Endocr Relat Cancer, 2006
DTC markers are listed and the most currently used of them (KRT19, CEACAM5, TACSTD1, MUC1, EGFR, ERBB2, SCGB2A2, SCGB2A1, SCGB1D2, PIP, SBEM, TFF1, TFF3, ANKRD30A, SPDEF, ESR1, SERPINB5 and GABRP) are discussed, notably on the basis of recent data on breast tumour portraits (luminal epithelial-like, basal/myoepithelial-like and ERBB2).
Mammaglobin is associated with low-grade, steroid receptor-positive breast tumors from postmenopausal patients, and has independent prognostic value for relapse-free survival time.
Impact
Sweep et al., Nijmegen, Netherlands. In J Clin Oncol, 2004
PURPOSE: The tumor mRNA expression levels of mammaglobin, a novel breast-specific and breast cancer-associated marker, were correlated with disease outcome in 280 patients with primary breast cancer.
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