Prioritization of Candidate Genes for Periodontitis Using Multiple Computational Tools.
Harbin, China. In J Periodontol, 02 Mar 2014
However, the roles of other genes, such as CSF3, CD40, TNFSF14, IFNB1, TIRAP, IL2RA, ETS1, GADD45B, BIRC3, VAV1, COL5A1, and C3, had not been thoroughly investigated in the process of periodontitis.
RAGE in tissue homeostasis, repair and regeneration.
Perugia, Italy. In Biochim Biophys Acta, 2013
Upon RAGE ligation, adaptor proteins (i.e., diaphanous-1, TIRAP, MyD88 and/or other as yet unidentified adaptors) associate with RAGE cytoplasmic domain resulting in signaling.
[Negative regulation of Toll-like receptor signalling].
Lublin, Poland. In Postepy Hig Med Dosw (online), 2012
MyD88, TIRAP, TRIF, TRAM, and IPS-1, which participate in the cascade activation of kinases (IKK, MAP, RIP-1, TBK-1) as well as transcription factors (NF-κB, AP-1) and regulatory factor (IRF3).
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
Vancouver, Canada. In Nat Med, 2010
We show that deletion of chromosome 5q correlates with loss of two miRNAs that are abundant in hematopoietic stem/progenitor cells (HSPCs), miR-145 and miR-146a, and we identify Toll-interleukin-1 receptor domain-containing adaptor protein (TIRAP) and tumor necrosis factor receptor-associated factor-6 (TRAF6) as respective targets of these miRNAs.