Mal de Meleda: A Focused Review.
Reno, United States. In Am J Clin Dermatol, 08 Nov 2015
UNASSIGNED: Mal de Meleda is a rare autosomal recessive palmoplantar keratoderma (PPK) disease with an estimated prevalence of 1:100,000.
Editorial. Informed consent: the dawning of a new era.
In Br Dent J, 25 Oct 2015
Lord Justice Sedley in the case of Wyatt v Curtis  laid a foundation for this Supreme Court Ruling (Montgomery v Lanarkshire Health Board ), in that he argued there is 'something unreal about placing the onus of asking upon a patient who may not know that there is anything to ask about...'.
Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways.
Kyŏngsan, South Korea. In Apoptosis, Feb 2015
The Toll-like receptor/Interleukin (IL)-1 receptor (TLR/IL-1R) superfamily comprises proteins that contain the phylogenetically conserved Toll/IL-1 receptor (TIR) domain, which is responsible for the propagation of downstream signaling through recruitment of TIR domain containing cytosolic adaptor proteins such as MyD88, TIRAP/MAL, TRIF, TRAM and SARM.
Antiretroviral therapy and the kidney.
New York City, United States. In Top Antivir Med, Jun 2014
This article summarizes a presentation by Christina M. Wyatt, MD, at the IAS-USA continuing education program held in Washington, DC, in June 2013.
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
Vancouver, Canada. In Nat Med, 2010
We show that deletion of chromosome 5q correlates with loss of two miRNAs that are abundant in hematopoietic stem/progenitor cells (HSPCs), miR-145 and miR-146a, and we identify Toll-interleukin-1 receptor domain-containing adaptor protein (TIRAP) and tumor necrosis factor receptor-associated factor-6 (TRAF6) as respective targets of these miRNAs.