Olmsted syndrome: clinical, molecular and therapeutic aspects.
Paris, France. In Orphanet J Rare Dis, Dec 2014
OS has to be differentiated from other severe forms of PPK including Vohwinkel, Clouston, Papillon-Lefèvre or Haim-Munk syndromes, Mal de Meleda, pachyonychia congenita, Tyrosinemia type II and acrodermatitis enteropathica.
Antiretroviral therapy and the kidney.
New York City, United States. In Top Antivir Med, Jun 2014
This article summarizes a presentation by Christina M. Wyatt, MD, at the IAS-USA continuing education program held in Washington, DC, in June 2013.
Identification of miR-145 and miR-146a as mediators of the 5q- syndrome phenotype.
Vancouver, Canada. In Nat Med, 2010
We show that deletion of chromosome 5q correlates with loss of two miRNAs that are abundant in hematopoietic stem/progenitor cells (HSPCs), miR-145 and miR-146a, and we identify Toll-interleukin-1 receptor domain-containing adaptor protein (TIRAP) and tumor necrosis factor receptor-associated factor-6 (TRAF6) as respective targets of these miRNAs.