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Melanoma antigen family B, 4

MAGEB4
This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEB genes are clustered on chromosome Xp22-p21. This gene sequence ends in the first intron of MAGEB1, another family member. This gene is expressed in testis. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, MAGE-1, MAGE-B1, MAGE-B2, Mage-b3
Papers on MAGEB4
Two members of the human MAGEB gene family located in Xp21.3 are expressed in tumors of various histological origins.
Boon et al., Brussels, Belgium. In Genomics, 1998
It contains four MAGE-related genes, which we propose to name MAGE-B1, B2, B3, and B4 (HGMW-approved symbols MAGEB1, MAGEB2, MAGEB3, and MAGEB4).
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