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proteins. Page last changed on 19 Aug 2016.
Melanoma antigen family D, 2
MAGE-D, MAGE-D2, BcgI, breast cancer associated gene 1
This gene is a member of the MAGED gene family. While the MAGEA and MAGEB genes are silent in normal tissues with the exception of testis and placenta, the MAGED genes are expressed ubiquitously. The MAGED genes are clustered on chromosome Xp11. This gene is located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). Multiple alternatively spliced transcript variants have been found for this gene, however, the full length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] (from
Kodera et al., Nagoya, Japan. In Oncol Lett, Mar 2015
In the present study, the expression of the melanoma-associated antigen-D2 (MAGE-D2) gene was investigated to determine whether it affects the malignant phenotype of HCC and thus, may serve as a marker of prognosis.
Alshatwi et al., Riyadh, Saudi Arabia. In Asian Pac J Cancer Prev, 2012
We aimed at determining whether any association exists between single nucleotide polymorphisms in breast cancer associated gene 1 (BRCA1) and breast cancer associated gene 2 (BRCA2) and the risk of breast cancer.