Immunotherapy for melanoma.
Tampa, United States. In Curr Opin Oncol, 2011
The development of vaccines that include agonists of various immune signaling like the MAGE-3 ASCI has also revived the field of cancer vaccines.
Immunogenicity of human neuroblastoma.
Genova, Italy. In Ann N Y Acad Sci, 2004
Here we shall review the work carried out in our lab in recent years and show that NB cells express tumor-associated antigens, such as MAGE-3, but lack constitutive expression of costimulatory molecules and surface HLA class I and II molecules.
[Antitumor vaccines: conception, development and evaluation in humans].
France. In Ann Pharm Fr, 2002
A series of phase I/II clinical studies evaluating ALVAC recombinants carrying either the CEA, p53, MAGE1 or MAGE3 genes, administered through the subcutaneous, intradermal or intravenous routes, has shown that this approach is safe and can induce tumor-specific antibody or T cell responses in at least some of the patients.