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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Tubulin, beta class I

M40, TUBB
displays androgen dependent expression in prostate epithelial cells [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: HAD, OUT, fibrillin-1, CAN, iMpact
Papers on M40
Identification and localization of xylose-binding proteins as potential biomarkers for liver fibrosis/cirrhosis.
New
Li et al., Xi'an, China. In Mol Biosyst, Jan 2016
TUBB and MX1) were up-regulated in the activated HSCs. 2 candidates (i.e.
Mutations in Either TUBB or MAPRE2 Cause Circumferential Skin Creases Kunze Type.
New
Van Esch et al., Leuven, Belgium. In Am J Hum Genet, Jan 2016
Here, we report that mutations in either MAPRE2 or TUBB underlie the genetic origin of this syndrome.
Exercise-induced differential changes in gene expression among arterioles of skeletal muscles of obese rats.
New
Davis et al., United States. In J Appl Physiol, Oct 2015
SPRINT had effects on expression of Crem, Dhh, Bcl2l1, and Ubd that were similar to EX. SPRINT also increased expression of Nfkbia, Hspa5, Tubb 2a and Tubb 2b, and Fkbp5 in all five arterioles and increased expression of Gnat1 in all but the soleus second-order arterioles.
Moderate alterations of the cytoskeleton in human chondrocytes after short-term microgravity produced by parabolic flight maneuvers could be prevented by up-regulation of BMP-2 and SOX-9.
New
Grimm et al., Magdeburg, Germany. In Faseb J, Jun 2015
The mRNAs were significantly up-regulated as follows: TUBB, 2-fold; VIM, 1.3-fold; KRT8, 1.8-fold; ACTB, 1.9-fold; ICAM1, 4.8-fold; OPN, 7-fold; ITGA10, 1.5-fold; ITGB1, 1.2-fold; TGFB1, 1.5-fold; CAV1, 2.6-fold; SOX9, 1.7-fold; BMP-2, 5.3-fold.
Evaluation of Reference Genes for RT-qPCR in Tribolium castaneum (Coleoptera: Tenebrionidae) Under UVB Stress.
New
Lei et al., Wuhan, China. In Environ Entomol, Apr 2015
Ribosomal protein genes RpS3, RpL13A, and β-actin gene (ActB) showed the highest stability across all UVB irradiation time points, whereas expression of other normally used reference genes, such as those encoding the β-tubulin gene TUBB and the E-cadherin gene CAD, varied at different developmental stages.
[Screening of citrullinated proteins in ten tumor cell lines].
New
Chang et al., Jinan, China. In Zhonghua Zhong Liu Za Zhi, Mar 2015
RESULTS: 2-D WB and mass spectrometry identified citrullinated ENO1 (α-enolase), HSP60 (heat shock protein 60), KRT8 (keratin 8), TUBB (tubulin beta), TCRβ (T cell receptor β chain), VIME (vimentin) and PDI in these cell lines.
Mutations in α- and β-tubulin encoding genes: implications in brain malformations.
Review
New
Borgatti et al., Lecco, Italy. In Brain Dev, Mar 2015
Different mutations in α/β-tubulin genes (TUBA1A, TUBA8, TUBB2A, TUBB4A, TUBB2B, TUBB3, and TUBB) might alter the dynamic properties and functions of microtubules in several ways, effecting a reduction in the number of functional tubulin heterodimers and causing alterations in GTP binding and disruptions of the binding of other proteins to microtubules (motor proteins and other microtubule interacting proteins).
Functional relevance for multiple sclerosis-associated genetic variants.
Lei et al., Suzhou, China. In Immunogenetics, 2015
Among the 45 SNPs, 15 were predicted most likely located in transcription factor (TF) binding sites, and five predicted SNPs (rs3095329 of TUBB, rs9469220/rs2647046 of HLA-DQB1, rs11154801 of AHI1, and rs1062158 of NDFIP1) have corresponding target genes with significantly differential expressions in multiple cell groups, while rs7194 of HLA-DRA was predicted in the has-miR-6507-3p binding site.
The Proportion of Chromatin Graded between Closed and Open States Determines the Level of Transcripts Derived from Distinct Promoters in the CYP19 Gene.
Ishihara et al., Japan. In Plos One, 2014
While some of the promoters were silent, CYP19 mRNA production differed among the other promoters, whose estimated transcription levels were 0.001% to 0.1% of that of the TUBB control gene.
Mechanisms of three-dimensional growth of thyroid cells during long-term simulated microgravity.
Grimm et al., Magdeburg, Germany. In Sci Rep, 2014
In order to explain the different behaviour, we analyzed the gene expression of IL6, IL7, IL8, IL17, OPN, NGAL, VEGFA and enzymes associated cytoskeletal or membrane proteins (ACTB, TUBB, PFN1, CPNE1, TGM2, CD44, FLT1, FLK1, PKB, PKC, ERK1/2, Casp9, Col1A1) as well as the amount of secreted proteins (IL-6, IL-7, IL-8, IL-17, OPN, NGAL, VEGFA).
The dilution effect and the importance of selecting the right internal control genes for RT-qPCR: a paradigmatic approach in fetal sheep.
Braun et al., Berlin, Germany. In Bmc Res Notes, 2014
The usefulness of RNA18S, ACTB, HPRT1, RPLP0, PPIA and TUBB as ICGs was analyzed according to effects of early dexamethasone (DEX) treatment, gender, and gestational age by two approaches: (1) the classical approach where raw (i.e., not normalized) RT-qPCR data of tested ICGs were statistically analyzed and the best ICG selected based on absence of any significant effect; (2) used of published algorithms.
Selection of reference genes as internal controls for gene expression in tissues of red abalone Haliotis rufescens (Mollusca, Vetigastropoda; Swainson, 1822).
Del Río-Portilla et al., Ensenada, Mexico. In Gene, 2014
Stability of nine housekeeping genes (ACTB, BGLU, TUBB, CY, GAPDH, HPRTI, RPL5, SDHA and UBC) was evaluated in different tissues of red abalone (gill, head and gonad/digestive gland).
Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6.
Kobarg et al., Campinas, Brazil. In J Proteome Res, 2014
Notably, endogenous RGS2, TUBB, MNAT1, NEK9, and PLEKHA8 localized with NEK7 at key sites throughout the cell cycle, especially during mitosis and cytokinesis.
Modulation of proteome expression by F-type lectin during viral hemorrhagic septicemia virus infection in fathead minnow cells.
Kim et al., Kwangju, South Korea. In Fish Shellfish Immunol, 2014
The results suggest RbFTL-3 modulates the expression of proteins related to viral budding (SNF8, CCT5 and TUBB) and thrombin signaling (F2) to increase the viability of VHSV infected cells.
Identification of potential serum proteomic biomarkers for clear cell renal cell carcinoma.
Huang et al., Xi'an, China. In Plos One, 2013
Three candidate peaks, which were upregulated in ccRCC group and showed a tendency to return to healthy control values after surgery, were identified as peptide regions of RNA-binding protein 6 (RBP6), tubulin beta chain (TUBB), and zinc finger protein 3 (ZFP3) with the m/z values of 1466.98,
Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.
GeneRIF
Bahn et al., Cambridge, United Kingdom. In J Proteome Res, 2012
A protein encoded by this locus was found to be differentially expressed in postmortem brains from patients with atypical frontotemporal lobar degeneration.
Expression of β-tubulin isotypes in classical Hodgkin's lymphoma.
GeneRIF
Kim et al., Ansan, South Korea. In Pathol Int, 2012
Class II beta-tubulin may be very useful for immunohistochemical diagnosis of classical Hodgkin's lymphoma.
Regional differences in expression of β-tubulin isoforms in schizophrenia.
GeneRIF
McCullumsmith et al., Birmingham, United States. In Schizophr Res, 2012
The results od this study found that betaI-tubulin protein expression was decreased in the anterior cingulate cortex and increased in the dorsolateral prefrontal cortex, but not changed in superior temporal gyrus or hippocampus in schizophrenia.
βII-tubulin and βIII-tubulin mediate sensitivity to peloruside A and laulimalide, but not paclitaxel or vinblastine, in human ovarian carcinoma cells.
GeneRIF
Miller et al., Wellington, New Zealand. In Mol Cancer Ther, 2012
Data suggest that the increased betaII- and betaIII-tubulin contributed significantly to the resistance phenotype.
cGMP inhibits TGF-beta signaling by sequestering Smad3 with cytosolic beta2-tubulin in pulmonary artery smooth muscle cells.
GeneRIF
Chen et al., Birmingham, United States. In Mol Endocrinol, 2011
Smad3 was bound to beta2-tubulin in a TGF-beta1/cGMP-dependent manner.
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