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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Cadherin 15

M-cadherin, cadherin-14, CDH15
This gene is a member of the cadherin superfamily of genes, encoding calcium-dependent intercellular adhesion glycoproteins. Cadherins consist of an extracellular domain containing 5 cadherin domains, a transmembrane region, and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. The protein is thought to be essential for the control of morphogenetic processes, specifically myogenesis, and may provide a trigger for terminal muscle cell differentiation. [provided by RefSeq, Jul 2008] (from NCBI)
Papers using M-cadherin antibodies
Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population
Supplier
Simon András et al., In The Journal of Cell Biology, 2003
... Hybridoma Bank), mouse monoclonal anti–myosin heavy chain IgG (MF20; Developmental Studies Hybridoma Bank), mouse monoclonal anti–M-cadherin IgG (Clone 1B11 used for immunofluorescence; nanotools GmbH), rabbit polyclonal anti–collagen type IV antibody (Rockland Immunochemicals, Inc.), rabbit polyclonal ...
Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes
Supplier
Rudnicki Michael A. et al., In The Journal of Cell Biology, 1995
... ) and anti–M-cadherin antibody sc-6470 (Santa Cruz Biotechnology ...
Papers on M-cadherin
Suppression of GSK-3β activation by M-cadherin protects myoblasts against mitochondria-associated apoptosis during myogenic differentiation.
GeneRIF
Alway et al., Morgantown, United States. In J Cell Sci, 2011
Inhibition of GSK-3beta activation by M-cadherin protects myoblasts against mitochondria-associated apoptosis during myogenic differentiation.
Toxoplasma gondii down modulates cadherin expression in skeletal muscle cells inhibiting myogenesis.
GeneRIF
Barbosa et al., Rio de Janeiro, Brazil. In Bmc Microbiol, 2010
These data suggest that Toxoplasma gondii is able to down regulate M-cadherin expression, leading to molecular modifications in the host cell surface that interfere with membrane fusion and consequently affect the myogenesis process.
Myogenic regulatory factors regulate M-cadherin expression by targeting its proximal promoter elements.
GeneRIF
Chen et al., Taiwan. In Biochem J, 2010
Observations identify a molecular mechanism by which MRFs regulate M-cadherin expression directly to ensure the terminal differentiation of myoblasts.
Alterations in CDH15 and KIRREL3 in patients with mild to severe intellectual disability.
GeneRIF
Srivastava et al., Greenwood, United States. In Am J Hum Genet, 2008
Alterations in CDH15 in patients with mild to severe intellectual disability are reported.
Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.
Impact
GeneRIF
Kachar et al., Los Angeles, United States. In Nature, 2007
Biochemical experiments show that CDH23 homodimers interact in trans with PCDH15 homodimers to form a filament with structural similarity to tip links
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