Synthesis, in vitro antimycobacterial evaluation and docking studies of some new 5,6,7,8-tetrahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one schiff bases.
Warangal, India. In Bioorg Med Chem Lett, Jan 2016
The compounds 6b, 6c, 6d, 6k, 7b, 7c, 7d and 7k exhibited promising antibacterial activity MIC in the range of 15-73μM against all bacterial strains used and compounds 6d and 7b showed antimycobacterial activity (IC50 <340μM in LRP assay) and (MIC <9μM in broth microdilution method).
An update on laboratory diagnosis in myasthenia gravis.
Vancouver, Canada. In Clin Chim Acta, Oct 2015
They also describe the methods to measure each of the specific antibodies that have recently permitted to split the diagnosis: Abs to omega-conotoxin receptor in Lambert Eaton Myasthenic Syndrome (LEMS), abs to the acetylcholine receptor (AchR) in MG, Abs to muscle specific tyrosine kinase (MuSK) in Ab negative MG, and Abs to low molecular weight receptor related low-density lipo protein-4 (LRP-4).
LRP receptor family member associated bone disease.
Kansas City, United States. In Rev Endocr Metab Disord, Jun 2015
In this review we discuss some of the most recent reports (in the past 2 years) highlighting the involvement of the members of the LRP family (LRP5, LRP6, LRP4, and more recently LRP8) in the maintenance of bone and their implications in bone diseases.