gopubmed logo
 
find other proteinsAll proteins
GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

CAMP responsive element binding protein 3-like 4

LZIP, Luman, JAL, CREB3, CREB3L4
This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] (from NCBI)
Top mentioned proteins: CREB, ATF6, Host Cell Factor C1, ACID, CAN
Papers on LZIP
Luman is involved in osteoclastogenesis through the regulation of DC-STAMP expression, stability and localization.
New
Imaizumi et al., Shiojiri, Japan. In J Cell Sci, Jan 2016
Luman (also known as CREB3) is a type-II transmembrane transcription factor belonging to the OASIS family that localizes to the endoplasmic reticulum (ER) membrane under normal conditions.
IL-10 and integrin signaling pathways are associated with head and neck cancer progression.
New
McWeeney et al., Portland, United States. In Bmc Genomics, Dec 2015
An 11-gene signature derived from a combination of unique mutations and differential expression was identified (PAGE4, SMTNL1, VTN, CA5A, C1orf43, KRTAP19-1, LEP, HRH4, PAGE5, SEZ6L, CREB3).
The Unfolded Protein Response and Cholesterol Biosynthesis Link Luman/CREB3 to Regenerative Axon Growth in Sensory Neurons.
New
Verge et al., Saskatoon, Canada. In J Neurosci, Nov 2015
UNLABELLED: We recently revealed that the axon endoplasmic reticulum resident transcription factor Luman/CREB3 (herein called Luman) serves as a unique retrograde injury signal in regulation of the intrinsic elongating form of sensory axon regeneration.
Expression patterns of immune-associated genes in external genital and perianal warts treated with sinecatechins.
New
Tyring et al., Houston, United States. In Viral Immunol, May 2015
Genes that were significantly regulated between VRs and VNRs were CREB3L4, HIST1H3A, HIST1H3H, IFNA1, IFNA4, IFNA5, IFNA6, IFNA8, IFNA14, IFNG, IFNAR1, IL6, IRF9, MAPK4, MAPK5, MAPK14, NET1, and PIK3C2A in the IFN array.
Transcriptional regulation of secretory capacity by bZip transcription factors.
New
Andrew et al., Baltimore, United States. In Front Biol, Mar 2015
These include components of the three canonical branches of the UPR-ATF4, XBP1, and ATF6, as well as the five members of the Creb3 family of transcription factors.
Expression and localization of Luman/CREB3 in mouse embryos during the pre-implantation period.
Jin et al., Sedan, France. In Genet Mol Res, 2014
Luman/CREB3 is a transcription factor that is a member of the cAMP-response-element-binding protein family of basic region-leucine zipper transcription factors.
Expression Patterns of CREBs in Oocyte Growth and Maturation of Fish.
Nagahama et al., Hyderābād, India. In Plos One, 2014
In addition, a 3'UTR variant form, CREB3 was exclusively found in ovary.
Effects of low-fat diet and aging on metabolic profiles of Creb3l4 knockout mice.
Ahn et al., Seoul, South Korea. In Nutr Diabetes, 2014
Previously, we reported that CREB3L4 expressed in adipose tissue negatively regulates adipogenesis, and Creb3l4 knockout mice fed a high-fat diet for 16 weeks showed fat cell hyperplasia, with improved glucose tolerance and insulin sensitivity.
Microarray-based identification of differentially expressed genes in extramammary Paget's disease.
Xu et al., Shanghai, China. In Int J Clin Exp Med, 2014
Real-time PCR was conducted to verify the differential expression of some representative genes, including ERBB4, TCF3, PAPSS2, PIK3R3, PRLR, SULT1A1, TCF7L1, and CREB3L4.
Physiological functions of endoplasmic reticulum stress transducer OASIS in central nervous system.
Review
Saito, Hiroshima, Japan. In Anat Sci Int, 2014
These membrane-bound bZIP transcription factors include OASIS, BBF2H7 CREBH, CREB4 and Luman, and are collectively referred to as OASIS family members.
Identification of Creb3l4 as an essential negative regulator of adipogenesis.
Ahn et al., Seoul, South Korea. In Cell Death Dis, 2013
In this study, we investigated the role of CREB3L4, a member of the CREB3-like family, in the regulation of adiposity.
A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens.
Impact
Sabatini et al., Cambridge, United States. In Nat Cell Biol, 2013
Furthermore, ARF4 expression is induced when cells are exposed to several Golgi-disturbing agents and requires the CREB3 (also known as Luman or LZIP) transcription factor, whose downregulation mimics ARF4 loss.
Analysis of genes regulated by the transcription factor LUMAN identifies ApoA4 as a target gene in dendritic cells.
GeneRIF
Adema et al., Nijmegen, Netherlands. In Mol Immunol, 2012
Data show that ApoA4 is a true target gene of LUMAN in bone marrow-derived DCs (BMDCs).
Regulation of ADP-ribosylation factor 4 expression by small leucine zipper protein and involvement in breast cancer cell migration.
GeneRIF
Ko et al., Seoul, South Korea. In Cancer Lett, 2012
sLZIP-regulated ARF4 expression in response to phorbol 12-myristate 13-acetate is involved in breast cancer cell migration.
Human leucine zipper protein sLZIP induces migration and invasion of cervical cancer cells via expression of matrix metalloproteinase-9.
GeneRIF
Ko et al., Seoul, South Korea. In J Biol Chem, 2012
sLZIP plays a critical role in MMP-9 expression and is probably involved in invasion and metastasis of cervical cancer
The signalling from endoplasmic reticulum-resident bZIP transcription factors involved in diverse cellular physiology.
Review
Imaizumi et al., Hiroshima, Japan. In J Biochem, 2011
These membrane-bound bZIP transcription factors include Luman, OASIS, BBF2H7, CREBH and CREB4.
Physiological unfolded protein response regulated by OASIS family members, transmembrane bZIP transcription factors.
Review
Imaizumi et al., Hiroshima, Japan. In Iubmb Life, 2011
OASIS family proteins include OASIS, BBF2H7, CREBH, AIbZIP, and Luman.
HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells.
GeneRIF
Yoon et al., Seoul, South Korea. In Cell Mol Life Sci, 2010
These findings suggest that HDAC3 selectively represses CREB3-mediated transcriptional activation and chemotactic signalling in human metastatic breast cancer cells.
DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation.
GeneRIF
Adema et al., Nijmegen, Netherlands. In Mol Immunol, 2010
DC-STAMP interacts with ER-resident transcription factor LUMAN which becomes activated during DC maturation.
Androgen-regulated transcription factor AIbZIP in prostate cancer.
Review
Calvo et al., Québec, Canada. In J Steroid Biochem Mol Biol, 2008
Androgen-induced bZIP (AIbZIP/CREB3L4) is a transcription factor of the bZIP family that associates with the membrane of the endoplasmic reticulum (ER).
share on facebooktweetadd +1mail to friends