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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Apolipoprotein F

LTIP, apolipoprotein F, apoF, Lipid transfer inhibitor protein
The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HDL, CETP, fibrillin-1, apolipoprotein E, HAD
Papers on LTIP
Human plasma protein N-glycosylation.
New
Wuhrer et al., Leiden, Netherlands. In Glycoconj J, Dec 2015
Thus, as the assessment of protein glycosylation is becoming a major element in clinical and biopharmaceutical research, this review aims to convey the current state of knowledge on the N-glycosylation of the major plasma glycoproteins alpha-1-acid glycoprotein, alpha-1-antitrypsin, alpha-1B-glycoprotein, alpha-2-HS-glycoprotein, alpha-2-macroglobulin, antithrombin-III, apolipoprotein B-100, apolipoprotein D, apolipoprotein F, beta-2-glycoprotein 1, ceruloplasmin, fibrinogen, immunoglobulin (Ig) A, IgG, IgM, haptoglobin, hemopexin, histidine-rich glycoprotein, kininogen-1, serotransferrin, vitronectin, and zinc-alpha-2-glycoprotein. In addition, the less abundant immunoglobulins D and E are included because of their major relevance in immunology and biopharmaceutical research.
Transcriptional regulation of the apolipoprotein F (ApoF) gene by ETS and C/EBPα in hepatoma cells.
New
Lin et al., Fuzhou, China. In Biochimie, May 2015
Apolipoprotein F (ApoF) inhibits cholesteryl ester transfer protein (CETP) activity and plays an important role in lipid metabolism.
Comparative study of serum proteomes in Legg-Calve-Perthes disease.
Bai et al., Xi'an, China. In Bmc Musculoskelet Disord, 2014
Including higher abundances of complement factor H (1.44), complement C4-B (1.45), isocitrate dehydrogenase [NAD] subunit alpha (2.7) alpha-1-acid glycoprotein 1 (1.87), heptoglobin (1.53) and Ig lambda-2 chain C regions (1.46), and lower levels of apolipoprotein E (0.50), apolipoprotein F (0.60), apolipoprotein C-III (0.69), S100-A8 (0.73), S100-A9 (0.75) and prothrombin (0.77) in LCPD than in controls.
Inter-alpha-trypsin inhibitor heavy chain 4: a novel biomarker for environmental exposure to particulate air pollution in patients with chronic obstructive pulmonary disease.
Chuang et al., Taipei, Taiwan. In Int J Chron Obstruct Pulmon Dis, 2014
Biomarkers for PM10 in COPD were identified and compared with the same in healthy controls and included proteoglycan 4 (PRG4), inter-alpha-trypsin inhibitor heavy chain 4 (ITIH4), and apolipoprotein F (APOF).
Retinoic acid regulates several genes in bile acid and lipid metabolism via upregulation of small heterodimer partner in hepatocytes.
Subauste et al., Jackson, United States. In Gene, 2014
In the present study, we have identified several critical genes in lipid homeostasis (Apoa1, Apoa2 and ApoF) that are repressed by RA-treatment in a SHP dependent manner, in vitro and also in vivo with the use of the SHP null mice.
Absolute quantification of apolipoproteins and associated proteins on human plasma lipoproteins.
Kleffmann et al., Dunedin, New Zealand. In J Proteomics, 2014
The most distinct differences were seen in the abundance of all apoCs, apoE and apoF.
The composition and metabolism of large and small LDL.
Review
Schaefer et al., Boston, United States. In Curr Opin Lipidol, 2014
Proteins associated with LDL, in addition to apolipoprotein (apo) B, include the C apolipoproteins, apoA-I, apoA-IV, apoD, apoE, apoF, apoH, apoJ, apoL-1, apoM, α-1 antitrypsin, migration inhibitory factor-related protein 8, lysosome C, prenylcysteine oxidase 1, paraoxonase 1, transthyretin, serum amyloid A4, and fibrinogen α chain.
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis.
Rader et al., Philadelphia, United States. In Atherosclerosis, 2014
Apolipoprotein F (ApoF) is a sialoglycoprotein that is a component of the HDL and LDL fractions of human serum.
The response of hepatic transcriptome to dietary cholesterol in Prague hereditary hypercholesterolemic (PHHC) rat.
Kovář et al., Praha, Czech Republic. In Physiol Res, 2013
Two of those genes, Apof and Aldh1a7, were studied in more detail, and their role in pathogenesis of hypercholesterolemia in PHHC rats could not been corroborated.
Farnesoid X receptor up-regulates expression of lipid transfer inhibitor protein in liver cells and mice.
Jiang et al., Chongqing, China. In Biochem Biophys Res Commun, 2013
Apolipoprotein F is a component protein mainly secreted by liver and resides on several lipoprotein classes.
Dynamic nuclear polarization of sedimented solutes.
Bertini et al., Sesto Fiorentino, Italy. In J Am Chem Soc, 2013
Using the 480 kDa iron-storage protein complex, apoferritin (ApoF), as an example, we demonstrate that sizable dynamic nuclear polarization (DNP) enhancements can be obtained on sedimented protein samples.
Clinical significance of plasma apolipoprotein F in Japanese healthy and hypertriglyceridemic subjects.
Hattori et al., Saitama, Japan. In J Atheroscler Thromb, 2012
AIM: Apolipoprotein F (apo F), also known as lipid transfer inhibitory protein (LTIP), is a protein component of plasma lipoprotein classes including HDL and functions to inhibit lipid transfer between lipoproteins in vitro.
The effects of apolipoprotein F deficiency on high density lipoprotein cholesterol metabolism in mice.
GeneRIF
Rader et al., Philadelphia, United States. In Plos One, 2011
Deletion of ApoF had no substantial impact on plasma lipid concentrations, high density lipoprotein cholesterol size, lipid or protein composition.
Conversion of lipid transfer inhibitor protein (apolipoprotein F) to its active form depends on LDL composition.
GeneRIF
Greene et al., Cleveland, United States. In J Lipid Res, 2011
LTIP translocation is dependent on LDL lipid composition
Proteomic analysis of electronegative low-density lipoprotein.
Sánchez-Quesada et al., Barcelona, Spain. In J Lipid Res, 2010
Statistical analysis of proteomic data indicated that the content of apoE, apoA-I, apoC-III, apoA-II, apoD, apoF, and apoJ was higher in LDL⁻ than in LDL(+).
Overexpression of apolipoprotein F reduces HDL cholesterol levels in vivo.
GeneRIF
Rader et al., Philadelphia, United States. In Arterioscler Thromb Vasc Biol, 2009
Overexpression of murine ApoF significantly reduced total cholesterol levels by 28%, high density lipoproteins by 27% and phospholipid levels by 19%.
Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex.
GeneRIF
Morton et al., Cleveland, United States. In J Lipid Res, 2008
lipoprotein composition may influence the status of lipid transfer inhibitor protein activity
Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects.
GeneRIF
Paromov et al., Cleveland, United States. In J Lipid Res, 2008
we have confirmed the negative association between plasma triglyceride levels and Apolipoprotein F previously suggested by a small data set, but now we demonstrate that this effect is seen only in males.
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