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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Leucine rich repeat containing 3B

Top mentioned proteins: NotI, SET, HAD, POLYMERASE, RPL15
Papers on LRP15
LRRC3B is downregulated in non-small-cell lung cancer and inhibits cancer cell proliferation and invasion.
He et al., Shenyang, China. In Tumour Biol, Sep 2015
UNASSIGNED: LRRC3B has emerged as a tumor suppressor in several human cancers.
The clinical value of LRRC3B gene expression and promoter hypermethylation in breast carcinomas.
Zhong et al., Guilin, China. In Cell Biochem Biophys, 2014
LRRC3B is a potential tumor suppressor gene newly discovered; however, the specific biologic function is still unknown.
Epigenetic silencing of BTB and CNC homology 2 and concerted promoter CpG methylation in gastric cancer.
Kim et al., Taejŏn, South Korea. In Cancer Lett, 2014
Furthermore, BACH2 promoter methylation paralleled that of previously identified targets, such as LRRC3B, LIMS2, PRKD1 and POPDC3, in a given set of gastric tumors.
Activity-dependent genes in mouse olfactory sensory neurons.
McClintock et al., Lexington, United States. In Chem Senses, 2014
Both unilateral naris occlusion of mice for 6 days and genetic silencing of OSNs decreased S100A5, Lrrc3b, Kirrel2, Slc17a6, Rasgrp4, Pcp4l1, Plcxd3, and Kcnn2 while increasing Kirrel3.
Validation of nucleolar protein 4 as a novel methylated tumor suppressor gene in head and neck cancer.
Califano et al., İstanbul, Turkey. In Oncol Rep, 2014
In the present study, we assessed the association of epigenetic alterations of a panel of 12 genes [nucleolar protein 4 (NOL4), iroquois homeobox 1 (IRX1), SLC5A8, LRRC3B, FUSSEL18, EBF3, GBX2, HMX2, SEPT9, ALX3, SOCS3 and LHX6] with head and neck squamous cell carcinoma (HNSCC) via a candidate gene approach.
Epigenetic alterations of chromosome 3 revealed by NotI-microarrays in clear cell renal cell carcinoma.
Kashuba et al., Moscow, Russia. In Biomed Res Int, 2013
These genes include tumor suppressors or candidates (VHL, CTDSPL, LRRC3B, ALDH1L1, and EPHB1) and genes that were not previously considered as cancer-associated (e.g., LRRN1, GORASP1, FGD5, and PLCL2).
Novel tumor suppressor candidates on chromosome 3 revealed by NotI-microarrays in cervical cancer.
Zabarovsky et al., Moscow, Russia. In Epigenetics, 2013
Thirty genes, including tumor suppressors or candidates (for example, VHL, RBSP3/CTDSPL, ITGA9, LRRC3B, ALDH1L1, EPHB1) and genes previously unknown as cancer-associated (ABHD5, C3orf77, PRL32, LOC285375, FGD5 and others), showed methylation/deletion in 21-44% of tumors.
Transcriptome analysis of duck liver and identification of differentially expressed transcripts in response to duck hepatitis A virus genotype C infection.
Yue et al., Chengdu, China. In Plos One, 2012
Of the 20 unigenes, nine matched the known genes in the database, including three up-regulated genes (virus replicase polyprotein, LRRC3B, and PCK1) and six down-regulated genes (CRP, AICL-like 2, L1CAM, CYB26A1, CHAC1, and ADAM32).
LRRC3B gene is frequently epigenetically inactivated in several epithelial malignancies and inhibits cell growth and replication.
Zabarovsky et al., Stockholm, Sweden. In Biochimie, 2012
Data suggest that LRRC3B gene could be involved in the process of carcinogenesis as a tumor suppressor gene.
Genetic and epigenetic analysis of non-small cell lung cancer with NotI-microarrays.
Zabarovsky et al., Stockholm, Sweden. In Epigenetics, 2012
A comprehensive statistical analysis suggested the set of 19 gene markers, ANKRD28, BHLHE40, CGGBP1, RBSP3, EPHB1, FGD5, FOXP1, GORASP1/TTC21, IQSEC1, ITGA9, LOC285375, LRRC3B, LRRN1, MITF, NKIRAS1/RPL15, TRH, UBE2E2, VHL, WNT7A, to allow early detection, tumor progression, metastases and to discriminate between SCC and ADC with sensitivity and specificity of 80-100%.
Methylation pattern of the putative tumor-suppressor gene LRRC3B promoter in clear cell renal cell carcinomas.
Kashuba et al., Kiev, Ukraine. In Mol Med Report, 2012
The LRRC3B gene promoter was methylated in 43% of clear cell renal carcinoma samples.
NotI microarrays: novel epigenetic markers for early detection and prognosis of high grade serous ovarian cancer.
Zabarovsky et al., Stockholm, Sweden. In Int J Mol Sci, 2011
To check the results of NMA hybridizations several samples for four genes (LRRC3B, THRB, ITGA9 and RBSP3 (CTDSPL)) were bisulfite sequenced and confirmed the results of NMA hybridization.
Odor-evoked gene regulation and visualization in olfactory receptor neurons.
Reed et al., Baltimore, United States. In Mol Cell Neurosci, 2010
One gene, Lrrc3b, was regulated more than 10-fold by odorant activity.
Epigenetic silencing of LRRC3B in colorectal cancer.
Fang et al., Shanghai, China. In Scand J Gastroenterol, 2008
LRRC3B may be a novel methylation-sensitive tumor suppressor gene in CRC. LRRC3B methylation has significant tumor specificity and may be a biomarker of CRC.
LRRC3B, encoding a leucine-rich repeat-containing protein, is a putative tumor suppressor gene in gastric cancer.
Kim et al., Taejŏn, South Korea. In Cancer Res, 2008
suggest that LRRC3B is a putative tumor suppressor gene that is silenced in gastric cancers by epigenetic mechanisms and that LRRC3B silencing in cancer may play an important role in tumor escape from immune surveillance
The novel gene LRP15 is regulated by DNA methylation and confers increased efficiency of DNA repair of ultraviolet-induced DNA damage.
Lu et al., Shanghai, China. In Bmb Rep, 2008
The expression of LRP15 is controlled by methylation in its promoter in HeLa cells, and LRP15 confers resistance to ultraviolet rays damage and accelerates the DNA repair rate.
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