Serum Biomarkers of Allergic Contact Dermatitis: A Pilot Study.
Vilnius, Lithuania. In Int Arch Allergy Immunol, Feb 2016
RESULTS: Serum levels of adiponectin, chemokine (C-C motif) ligand 5 (CCL5), C-reactive protein (CRP), chitinase 3-like 1 (CHI3L1), complement factor D (CFD), endoglin, lipocalin-2, osteopontin, retinol-binding protein 4 (RBP4), and platelet factor 4 (PF4) were significantly higher, whereas levels of trefoil factor 3 (TFF3) were significantly lower, in ACD patients than in healthy controls.
Therapeutic Effect of Chrysin on Adenine-Induced Chronic Kidney Disease in Rats.
Muscat, Oman. In Cell Physiol Biochem, Feb 2016
RESULTS: Adenine lowered creatinine clearance and elevated the concentrations of urea, creatinine, plasma neutrophil gelatinase-associated lipocalin and urinary N-Acetyl-beta-D-glucosaminidase activity, and increased the concentrations of the uremic toxin indoxyl sulfate, in addition to some inflammatory cytokines.
Laboratory Animal Allergy in the Modern Era.
London, United Kingdom. In Curr Allergy Asthma Rep, Dec 2015
Recent evidence suggests that members of lipocalin allergens, such as Mus m 1, may act as immunomodulatory proteins, triggering innate immune receptors through toll-like receptors and promoting airway laboratory animal allergy.
Biomarkers of drug-induced acute kidney injury in the adult.
Brisbane, Australia. In Expert Opin Drug Metab Toxicol, Nov 2015
Novel biomarkers, accepted for early detection of drug-induced AKI (kidney injury molecule-1, neutrophil gelatinase-associated lipocalin and N-acetyl-β-d-glucosaminidase), may be useful additions in panels of biomarkers.
Structural similarities of human & mammalian lipocalins, and their function in innate immunity and allergy.
Madrid, Spain. In Allergy, Nov 2015
The amino acid identities, as well as their structures by superposition modeling were compared among human lipocalins, hLCN1 and hLCN2, and most important animal lipocalin allergens, such as Can f 2 and Can f 4 from dog, Fel d 4 from cats, Bos d 5 from cow's milk, Equ c 1 from horses and Mus m 1 from mice, all of them representing major allergens.
Acute Kidney Injury in Patients with Cirrhosis.
Birmingham, United States. In J Clin Transl Hepatol, Oct 2015
In this regard, novel serum and/or urinary biomarkers such as neutrophil gelatinase-associated lipocalin, interleukins-6 and 18, kidney injury molecule-1, fatty acid binding protein, and endothelin-1 are emerging with a potential for accurately differentiating common causes of AKI.
Tear lipocalin: structure and function.
Boston, United States. In Ocul Surf, 2011
Tear lipocalin (TLC) is a major protein in tears and has a large ligand-binding cavity that allows the lipocalin to bind an extensive and diverse set of lipophilic molecules.