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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 03 Dec 2014.

Vps20-associated 1 homolog

LIP5, Vta1, SBP1, Vta1p
C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Vps4, ACID, ATPase, CAN, SBP2
Papers on LIP5
Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: A novel mechanism of cancer-specific cytotoxicity of selenite.
Xiong et al., Wuhan, China. In Free Radic Biol Med, 28 Dec 2014
This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity.
Biochemical and Biophysical Characterization of the Selenium-binding and Reducing Site in Arabidopsis thaliana Homologue to Mammals Selenium-binding Protein 1.
Hugouvieux et al., Grenoble, France. In J Biol Chem, 14 Dec 2014
The function of selenium-binding protein 1 (SBP1), present in almost all organisms, has not yet been established.
Effect of weight loss on central systolic blood pressure in elderly community-dwelling persons.
Miki et al., Japan. In Hypertens Res, Oct 2014
Before and at the end of the 12-week training program, metabolic variables, and first peak radial systolic BP (SBP1) and second peak radial SBP (SBP2) as estimates of central SBP, were obtained.
Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.
Nielsen et al., Göteborg, Sweden. In Appl Environ Microbiol, Sep 2014
Several single-point mutations, including an S196I point mutation in the VTA1 gene coding for a protein involved in vacuolar sorting, were evaluated by introducing these to the starting strain.
Only a subset of the PAB1-mRNP proteome is present in mRNA translation complexes.
Denis et al., Durham, United Kingdom. In Protein Sci, Aug 2014
We assayed by AU-FDS analysis 33 additional PAB1-mRNP factors but found that only five of these proteins were present in the 77S translation complex: eRF1, SLF1, SSD1, PUB1, and SBP1.
Arabidopsis LIP5, a positive regulator of multivesicular body biogenesis, is a critical target of pathogen-responsive MAPK cascade in plant basal defense.
Chen et al., Hangzhou, China. In Plos Pathog, Jul 2014
Membrane dissociation of ESCRTs is catalyzed by the AAA ATPase SKD1, which is stimulated by LYST-interacting protein 5 (LIP5).
Agonist-induced GPCR shedding from the ciliary surface is dependent on ESCRT-III and VPS4.
Jin et al., Chicago, United States. In Curr Biol, Apr 2014
VPAC2 ectosome shedding is dependent on several components of endosomal sorting complexes required for transport (ESCRT), including a subset of ESCRT-III, VPS4, and LIP5.
A novel endosomal sorting complex required for transport (ESCRT) component in Arabidopsis thaliana controls cell expansion and development.
Otegui et al., Madison, United States. In J Biol Chem, Mar 2014
PROS interacts with both SKD1 and the SKD1-positive regulator LIP5/VTA1.
The oligomeric state of the active Vps4 AAA ATPase.
Hill et al., Salt Lake City, United States. In J Mol Biol, Mar 2014
The Vta1p activator binds hexameric yeast Vps4p without changing the oligomeric state of Vps4p, implying that the active Vta1p-Vps4p complex also contains a single hexameric ring.
Molecular cross-talk between members of distinct families of selenium containing proteins.
Diamond et al., Chicago, United States. In Mol Nutr Food Res, Jan 2014
One of these, selenium-binding protein 1 (SBP1), is a protein of unknown function that has been shown to be reduced in tumors of diverse tissue types as compared to the corresponding normal tissue.
Selenium-binding protein 1 as a tumor suppressor and a prognostic indicator of clinical outcome.
Diamond et al., Xinxiang, China. In Biomark Res, Jan 2014
Selenium-binding protein 1 (SBP1) is a member of an unusual class of selenium-containing proteins that may function as a tumor suppressor in multiple cancer types and whose levels have been shown to be lower in cancers as compared to corresponding normal tissues.
Evaluation of cadmium-induced nephrotoxicity using urinary metabolomic profiles in sprague-dawley male rats.
Kim et al., Pusan, South Korea. In J Toxicol Environ Health A, Dec 2013
High-dose CdCl2 (25 mg/kg) exposure also significantly elevated protein-based urinary biomarkers including osteopontin, monocyte chemoattractant protein-1 (MCP-1), kidney injury molecules-1 (Kim-1), and selenium-binding protein 1 (SBP1) in rat urine.
Identification of SFBB-containing canonical and noncanonical SCF complexes in pollen of apple (Malus × domestica).
Sassa et al., Matsudo, Japan. In Plos One, Dec 2013
Generally, the F-box protein forms an E3 ligase complex, SCF complex with Skp1, Cullin1 (CUL1) and Rbx1, however, in Petunia inflata, SBP1 (S-RNase binding protein1) was reported to play the role of Skp1 and Rbx1, and form an SCFSLF-like complex for ubiquitination of non-self S-RNases.
The maize AAA-type protein SKD1 confers enhanced salt and drought stress tolerance in transgenic tobacco by interacting with Lyst-interacting protein 5.
Wu et al., Zhengzhou, China. In Plos One, 2012
The interaction between ZmSKD1 and NtLIP5 (Lyst-Interacting Protein 5 homolog from Nicotiana tabacum) was confirmed by both yeast two-hybrid and immuno-precipitation assays; moreover, the α-helix-rich domain in the C-terminus of ZmSKD1 was identified to be required for its interaction with NtLIP5 using truncation mutations.
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein.
Yang et al., Chicago, United States. In Carcinogenesis, 2010
SP1 is present in reduced levels in several cancer types as compared with normal tissues, and lower levels are associated with poor clinical prognosis.
The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
Deen et al., Nijmegen, Netherlands. In J Mol Histol, 2010
LIP5 protein expression in a mouse tissue panel and various rodent and human tissues were studied.[LIP5]
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p.
Jensen et al., Pasadena, United States. In J Mol Biol, 2008
models in which Vps4p MIT and Vta1p domains engage endosomal sorting complex required for transport-III substrates above the bowl and help transfer them into the bowl to be pumped through the center of the dodecameric assembly
Structural basis of Vta1 function in the multivesicular body sorting pathway.
Xu et al., Ann Arbor, United States. In Dev Cell, 2008
mechanism of regulation by Vta1 in which the C-terminal domain stabilizes the ATP-dependent double ring assembly.
ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.
Katzmann et al., Rochester, United States. In Dev Cell, 2008
impact of Vta1 and ESCRT-III family members on Vps4 ATPase activity
Conservation of plasma regulatory proteins of the complement system in evolution: humans and fish.
Zipfel et al., Hamburg, Germany. In Exp Clin Immunogenet, 1999
The complement regulatory protein of barred sand bass, SBP1, is related to both the human alternative pathway regulator factor H, and to the classical pathway regulator C4bp, and displays regulatory activities in both human pathways.
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