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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 02 Oct 2014.

Vps20-associated 1 homolog

LIP5, Vta1, SBP1, Vta1p
C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Vps4, ATPase, ACID, CAN, SBP2
Papers on LIP5
Agonist-induced GPCR shedding from the ciliary surface is dependent on ESCRT-III and VPS4.
New
Jin et al., Chicago, United States. In Curr Biol, Apr 2014
VPAC2 ectosome shedding is dependent on several components of endosomal sorting complexes required for transport (ESCRT), including a subset of ESCRT-III, VPS4, and LIP5.
A novel endosomal sorting complex required for transport (ESCRT) component in Arabidopsis thaliana controls cell expansion and development.
New
Otegui et al., Madison, United States. In J Biol Chem, Mar 2014
PROS interacts with both SKD1 and the SKD1-positive regulator LIP5/VTA1.
The oligomeric state of the active Vps4 AAA ATPase.
New
Hill et al., Salt Lake City, United States. In J Mol Biol, Mar 2014
The Vta1p activator binds hexameric yeast Vps4p without changing the oligomeric state of Vps4p, implying that the active Vta1p-Vps4p complex also contains a single hexameric ring.
Molecular cross-talk between members of distinct families of selenium containing proteins.
New
Diamond et al., Chicago, United States. In Mol Nutr Food Res, Jan 2014
One of these, selenium-binding protein 1 (SBP1), is a protein of unknown function that has been shown to be reduced in tumors of diverse tissue types as compared to the corresponding normal tissue.
Selenium-binding protein 1 as a tumor suppressor and a prognostic indicator of clinical outcome.
New
Diamond et al., Xinxiang, China. In Biomark Res, Jan 2014
Selenium-binding protein 1 (SBP1) is a member of an unusual class of selenium-containing proteins that may function as a tumor suppressor in multiple cancer types and whose levels have been shown to be lower in cancers as compared to corresponding normal tissues.
Relief of autoinhibition enhances Vta1 activation of Vps4 via the Vps4 stimulatory element.
New
Katzmann et al., Rochester, United States. In J Biol Chem, Oct 2013
The Vta1 carboxyl-terminal Vta1 SBP1 Lip5 (VSL) domain stimulates Vps4 function by facilitating oligomerization of Vps4 into its active state.
Lipolytic system of the tomato pathogen Fusarium oxysporum f. sp. lycopersici.
New
Roncero et al., Córdoba, Spain. In Mol Plant Microbe Interact, Sep 2013
Deletion mutants in five lipase genes (lip1, lip2, lip3, lip5, and lip22) and in the regulatory genes ctf1 and ctf2 as well as a Δctf1Δctf2 double mutant were generated.
Selenium-binding protein 1 may decrease gastric cellular proliferation and migration.
New
Das et al., Hangzhou, China. In Int J Oncol, May 2013
It has been reported that suppression of selenium‑binding protein 1 (SBP1) occurs in many human malignancies which is considered to play an important role in cancer development and progression.
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transport.
Sundquist et al., Salt Lake City, United States. In J Biol Chem, 2013
The ESCRT-III and VPS4 ATPase complexes catalyze the membrane fission events associated with these processes, and the LIP5 protein helps regulate their interactions by binding directly to a subset of ESCRT-III proteins and to VPS4.
The maize AAA-type protein SKD1 confers enhanced salt and drought stress tolerance in transgenic tobacco by interacting with Lyst-interacting protein 5.
Wu et al., Zhengzhou, China. In Plos One, 2012
The interaction between ZmSKD1 and NtLIP5 (Lyst-Interacting Protein 5 homolog from Nicotiana tabacum) was confirmed by both yeast two-hybrid and immuno-precipitation assays; moreover, the α-helix-rich domain in the C-terminus of ZmSKD1 was identified to be required for its interaction with NtLIP5 using truncation mutations.
2D-DIGE to identify proteins associated with gestational diabetes in omental adipose tissue.
Lappas et al., Australia. In J Endocrinol, 2012
These were alpha-1-antitrypsin (AIAT (SERPINA 1)), annexin A5 (ANXA5), fatty acid-binding protein, adipocyte (FABP4), glutathione S-transferase P (GSTP (GSTP1)), heat-shock protein beta-1 (HSP27 (HSPB1)), lactate dehydrogenase B chain (LDHB), perilipin-1 (PLIN1), peroxiredoxin-6 (PRX6 (PRDX6)), selenium-binding protein 1 (SBP1) and vinculin (VINC (VCL)).
Decreased selenium-binding protein 1 enhances glutathione peroxidase 1 activity and downregulates HIF-1α to promote hepatocellular carcinoma invasiveness.
Fan et al., Shanghai, China. In Clin Cancer Res, 2012
PURPOSE: We aimed to characterize the role of selenium-binding protein 1 (SBP1) in hepatocellular carcinoma (HCC) invasiveness and underlying clinical significance.
Identification and characterization of genes related to the production of organic acids in yeast.
Yokoyama et al., Yokohama, Japan. In J Biosci Bioeng, 2012
Acetate, pyruvate, and succinate are produced by yeast fermentation in rich medium, and their production was affected by mutations of the genes GTR1, GTR2, LIP5, LSM1, PHO85, PLM2, RTG1, RTG2 and UBP3, and also succinate dehydrogenase-related genes including EMI5, SDH1, SDH2, SDH4, TCM62 and YDR379C-A.
Strength of relationships of the pulse wave velocity and central hemodynamic indices with the serum N-terminal fragment B-type natriuretic peptide levels in men: a worksite cohort study.
Yamashina et al., Tokyo, Japan. In Circ J, 2011
METHODS AND RESULTS: In a total of 2,657 male employees of a company (46±9 years old), the first and second peaks of the radial systolic pressure waveform (SBP1 and SBP2, respectively), the radial augmentation index (rAI), the PP2 (SBP2 minus the diastolic blood pressure), the brachial-ankle pulse wave velocity (baPWV), and the serum NT-pro BNP levels were measured.
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein.
GeneRIF
Yang et al., Chicago, United States. In Carcinogenesis, 2010
SP1 is present in reduced levels in several cancer types as compared with normal tissues, and lower levels are associated with poor clinical prognosis.
The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
GeneRIF
Deen et al., Nijmegen, Netherlands. In J Mol Histol, 2010
LIP5 protein expression in a mouse tissue panel and various rodent and human tissues were studied.[LIP5]
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p.
GeneRIF
Jensen et al., Pasadena, United States. In J Mol Biol, 2008
models in which Vps4p MIT and Vta1p domains engage endosomal sorting complex required for transport-III substrates above the bowl and help transfer them into the bowl to be pumped through the center of the dodecameric assembly
Structural basis of Vta1 function in the multivesicular body sorting pathway.
GeneRIF
Xu et al., Ann Arbor, United States. In Dev Cell, 2008
mechanism of regulation by Vta1 in which the C-terminal domain stabilizes the ATP-dependent double ring assembly.
ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.
GeneRIF
Katzmann et al., Rochester, United States. In Dev Cell, 2008
impact of Vta1 and ESCRT-III family members on Vps4 ATPase activity
Conservation of plasma regulatory proteins of the complement system in evolution: humans and fish.
Review
Zipfel et al., Hamburg, Germany. In Exp Clin Immunogenet, 1999
The complement regulatory protein of barred sand bass, SBP1, is related to both the human alternative pathway regulator factor H, and to the classical pathway regulator C4bp, and displays regulatory activities in both human pathways.
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