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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 15 Jun 2015.

Vps20-associated 1 homolog

LIP5, Vta1, SBP1, Vta1p
C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008] (from NCBI)
Top mentioned proteins: Vps4, ATPase, ACID, CAN, SBP2
Papers on LIP5
Interactions between Plasmodium falciparum skeleton-binding protein 1 and the membrane skeleton of malaria-infected red blood cells.
New
Cooke et al., Australia. In Biochim Biophys Acta, 31 Jul 2015
We have previously shown that a resident MC protein, skeleton-binding protein 1 (SBP1), is essential for the placement of PfEMP1 onto the RBC surface and hypothesised that the function of SBP1 may be to target MCs to the RBC membrane.
Chromosome VIII disomy influences the nonsense suppression efficiency and transition metal tolerance of the yeast Saccharomyces cerevisiae.
New
Inge-Vechtomov et al., Saint Petersburg, Russia. In Yeast, 30 Jun 2015
We identified SBP1, a gene that localizes to chromosome VIII, as a dosage-dependent antisuppressor that strongly contributes to the overall antisuppressor effect of chromosome VIII disomy.
Distinct mechanisms of recognizing endosomal sorting complex required for transport III (ESCRT-III) protein IST1 by different microtubule interacting and trafficking (MIT) domains.
New
Xu et al., Ann Arbor, United States. In J Biol Chem, Apr 2015
In mammalian cells, efficient abscission during cytokinesis requires proper function of the ESCRT-III protein IST1, which binds to the microtubule interacting and trafficking (MIT) domains of VPS4, LIP5, and Spartin via its C-terminal MIT-interacting motif (MIM).
A novel mechanism of regulating the ATPase VPS4 by its cofactor LIP5 and the endosomal sorting complex required for transport (ESCRT)-III protein CHMP5.
New
Xu et al., Ann Arbor, United States. In J Biol Chem, Apr 2015
This reaction is catalyzed by VPS4, an AAA-ATPase whose activity is tightly regulated by a host of proteins, including LIP5 and the ESCRT-III proteins.
Reduction of selenium-binding protein 1 sensitizes cancer cells to selenite via elevating extracellular glutathione: a novel mechanism of cancer-specific cytotoxicity of selenite.
New
Xiong et al., Wuhan, China. In Free Radic Biol Med, Feb 2015
This study was to investigate the roles of two distinct representatives of selenium-containing proteins, selenium-binding protein 1 (SBP1) and glutathione peroxidase 1 (GPX1), in selenite-mediated cancer-specific cytotoxicity.
Evidence that selenium binding protein 1 is a tumor suppressor in prostate cancer.
New
Diamond et al., Chicago, United States. In Plos One, Dec 2014
Selenium-Binding Protein 1 (SBP1, SELENBP1, hSP56) is a selenium-associated protein shown to be at lower levels in tumors, and its lower levels are frequently predictive of a poor clinical outcome.
Quantitative proteomic analysis reveals that anti-cancer effects of selenium-binding protein 1 in vivo are associated with metabolic pathways.
New
Bie et al., Nanjing, China. In Plos One, Dec 2014
Previous studies have shown the tumor-suppressive role of selenium-binding protein 1 (SBP1), but the underlying mechanisms are unclear.
The Subcellular Location of Selenoproteins and the Impact on Their Function.
Review
New
Diamond, Chicago, United States. In Nutrients, Dec 2014
Each of these proteins have been described to reside in two or more cellular compartments, and in the case of GPx-1 and SBP1, interact with each other.
Biochemical and biophysical characterization of the selenium-binding and reducing site in Arabidopsis thaliana homologue to mammals selenium-binding protein 1.
New
Hugouvieux et al., Grenoble, France. In J Biol Chem, Dec 2014
The function of selenium-binding protein 1 (SBP1), present in almost all organisms, has not yet been established.
Effect of weight loss on central systolic blood pressure in elderly community-dwelling persons.
New
Miki et al., Japan. In Hypertens Res, Oct 2014
Before and at the end of the 12-week training program, metabolic variables, and first peak radial systolic BP (SBP1) and second peak radial SBP (SBP2) as estimates of central SBP, were obtained.
Improved production of a heterologous amylase in Saccharomyces cerevisiae by inverse metabolic engineering.
New
Nielsen et al., Göteborg, Sweden. In Appl Environ Microbiol, Sep 2014
Several single-point mutations, including an S196I point mutation in the VTA1 gene coding for a protein involved in vacuolar sorting, were evaluated by introducing these to the starting strain.
Arabidopsis LIP5, a positive regulator of multivesicular body biogenesis, is a critical target of pathogen-responsive MAPK cascade in plant basal defense.
New
Chen et al., Hangzhou, China. In Plos Pathog, Jul 2014
Membrane dissociation of ESCRTs is catalyzed by the AAA ATPase SKD1, which is stimulated by LYST-interacting protein 5 (LIP5).
Molecular cross-talk between members of distinct families of selenium containing proteins.
Review
Diamond et al., Chicago, United States. In Mol Nutr Food Res, 2014
One of these, selenium-binding protein 1 (SBP1), is a protein of unknown function that has been shown to be reduced in tumors of diverse tissue types as compared to the corresponding normal tissue.
Evaluation of cadmium-induced nephrotoxicity using urinary metabolomic profiles in sprague-dawley male rats.
Kim et al., Pusan, South Korea. In J Toxicol Environ Health A, 2013
High-dose CdCl2 (25 mg/kg) exposure also significantly elevated protein-based urinary biomarkers including osteopontin, monocyte chemoattractant protein-1 (MCP-1), kidney injury molecules-1 (Kim-1), and selenium-binding protein 1 (SBP1) in rat urine.
Functional and physical interaction between the selenium-binding protein 1 (SBP1) and the glutathione peroxidase 1 selenoprotein.
GeneRIF
Yang et al., Chicago, United States. In Carcinogenesis, 2010
SP1 is present in reduced levels in several cancer types as compared with normal tissues, and lower levels are associated with poor clinical prognosis.
The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
GeneRIF
Deen et al., Nijmegen, Netherlands. In J Mol Histol, 2010
LIP5 protein expression in a mouse tissue panel and various rodent and human tissues were studied.[LIP5]
Cryo-EM structure of dodecameric Vps4p and its 2:1 complex with Vta1p.
GeneRIF
Jensen et al., Pasadena, United States. In J Mol Biol, 2008
models in which Vps4p MIT and Vta1p domains engage endosomal sorting complex required for transport-III substrates above the bowl and help transfer them into the bowl to be pumped through the center of the dodecameric assembly
Structural basis of Vta1 function in the multivesicular body sorting pathway.
GeneRIF
Xu et al., Ann Arbor, United States. In Dev Cell, 2008
mechanism of regulation by Vta1 in which the C-terminal domain stabilizes the ATP-dependent double ring assembly.
ESCRT-III family members stimulate Vps4 ATPase activity directly or via Vta1.
GeneRIF
Katzmann et al., Rochester, United States. In Dev Cell, 2008
impact of Vta1 and ESCRT-III family members on Vps4 ATPase activity
Conservation of plasma regulatory proteins of the complement system in evolution: humans and fish.
Review
Zipfel et al., Hamburg, Germany. In Exp Clin Immunogenet, 1999
The complement regulatory protein of barred sand bass, SBP1, is related to both the human alternative pathway regulator factor H, and to the classical pathway regulator C4bp, and displays regulatory activities in both human pathways.
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