Beyaert et al., Gent, Belgium. In Biochem Pharmacol, 2009
This review defines ABIN-3 based on three different parameters: ability to bind A20; ability to inhibit NF-kappaB activation upon overexpression; the presence of specific short amino acid regions of strong homology, designated ABIN homology domains.
Schreiber et al., Saint Louis, United States. In Mol Cell Biol, 2007
ABIN-3 is, thus, an IL-10-induced gene product capable of attenuating NF-kappaB in human macrophages yet is inoperative in mice and represents a basis for species-specific differences in IL-10 actions.