Wakayama symposium: epithelial-mesenchymal interactions in eyelid development.
Okayama, Japan. In Ocul Surf, Oct 2012
These include FGFR2b-FGF10, EGFR-ERK, MEKK-JNK, BMP, Shh, Wnt, GPR48, Jun, Forkhead, and Grainyhead.
A finger on the pulse of Wnt receptor signaling.
Boston, United States. In Cell Res, Oct 2012
R-spondin binds to ZNRF3, in addition to transmembrane LGR4/5 receptors, to antagonize degradation of the Wnt receptors by ZNRF3, thereby resulting in increased Frizzled and LRP6 levels and a greater Wnt response.
GPR48 increases mineralocorticoid receptor gene expression.
Shanghai, China. In J Am Soc Nephrol, Feb 2012
We observed that G protein-coupled receptor 48 (Gpr48/Lgr4) hypomorphic mutant (Gpr48(m/m)) mice had hyperkalemia and increased water loss and salt excretion despite elevated plasma aldosterone levels, suggesting aldosterone resistance.