Cancer metabolism and mass spectrometry-based proteomics.
Manassas, United States. In Cancer Lett, Feb 2015
In addition, MS analyses from pancreatic cancer cells demonstrate that lactate dehydrogenase-B is significantly upregulated in pancreatic cancer cells, whereas previous reports show that lactate dehydrogenase-A is overexpressed and is responsible for lactate production in cancer cells.
Recruitment of enzymes and stress proteins as lens crystallins.
Bethesda, United States. In Exs, 1993
Some crystallins have been recruited without duplication of the original gene (i.e., lactate dehydrogenase B and alpha-enolase), while others have incurred one (i.e., argininosuccinate lyase and a small heat shock protein) or several (i.e., glutathione S-transferase) gene duplications.
Linkage of lactate dehydrogenase B and C loci in pigeons.
In Science, 1969
Synthesis of lactate dehydrogenase in somatic and gametic tissues of certain avian and mammalian species is controlled by alleles at three loci, A, B, and C. We report breeding experiments with pigeons that conclusively demonstrate linkage between the B and C structural loci in this species.