Enhancer-bound LDB1 regulates a corticotrope promoter-pausing repression program.
Hefei, China. In Proc Natl Acad Sci U S A, Mar 2015
Here we report the required actions of LIM domain-binding protein 1 (LDB1)/cofactor of LIM homeodomain protein 2/nuclear LIM interactor, interacting with the enhancer-binding protein achaete-scute complex homolog 1, to mediate looping to target gene promoters and target gene regulation in corticotrope cells.
Decoding the LIM development code.
In Trans Am Clin Climatol Assoc, 2002
The basic code is a homotetramer of 2 LIM homeodomain proteins bridged by the adaptor protein, nuclear LIM interactor (NLI).