Regulation of ceramide biosynthesis by TOR complex 2.
Davis, United States. In Cell Metab, 2008
Because Ypk2 is activated independently by LCBs, the direct precursors to ceramides, our data suggest a model wherein TORC2 signaling is coupled with LCB levels to control Ypk2 activity and, ultimately, regulate ceramide formation.
[Lyme borreliosis: underdiagnosed?--overtreated?].
Freiburg, Germany. In Monatsschr Kinderheilkd, 1990
B. burdorferi is also responsible for an early skin lesion, Borrelia lymphozytom [Lymphadenosis cutis benigna (LCB)], and for a late one, Acrodermatitis chronica atrophicans (ACA), both seen primarily in Europe.