Unexpected transcellular protein crossover occurs during canonical DNA transfection.
Cambridge, United Kingdom. In J Cell Biochem, 2014
Here, we demonstrate that Neuro2A cells transfected using Lipofectamine LTX with the fluorescently coupled Botulinum serotype A holoenzyme (EGFP-LcA) cDNA express this SNAP25 protease that can, once translated, escape the transfected host cytosol and become endocytosed into untransfected cells, without its innate binding and translocation domains.
The peptidoglycan recognition proteins LCa and LCx.
Boulder, United States. In Cell Mol Life Sci, 2007
Recent X-ray crystallographic studies of the peptidoglycan recognition proteins LCa, and LCx bound to peptidoglycan have provided structural insights into recognition of peptidoglycan and activation of innate immunity in insects.