Cell(s) of Origin of Langerhans Cell Histiocytosis.
Houston, United States. In Hematol Oncol Clin North Am, Oct 2015
Langerhans cell histiocytosis (LCH) is heterogeneous disease characterized by common histology of inflammatory lesions containing Langerin(+) (CD207) histiocytes.
The role of human dendritic cells in HIV-1 infection.
Cardiff, United Kingdom. In J Invest Dermatol, May 2015
DC studies have led to remarkable discoveries, including identification of restriction factors, cellular structures promoting viral transmission including the infectious synapse or the interplay of the C-type lectins, Langerin on Langerhans cells (LCs), and dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin on other DC subsets, limiting or facilitating HIV transmission to CD4(+) T cells, respectively.