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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Lysosomal-associated membrane protein 1

LAMP-1, CD107a, Lysosomal-Associated Membrane Protein 1
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, CD8, HAD, CD4, V1a
Papers using LAMP-1 antibodies
Studying lipids involved in the endosomal pathway.
Johannes Ludger, In PLoS ONE, 2011
... South San Francisco, CA); EEA1 (Transduction Laboratories); LAMP1 (CD107a; BD Biosciences); EGFR (BD Biosciences); α-tubulin ...
CD3 limits the efficacy of TCR gene therapy in vivo.
Rodrigues Mauricio Martins, In PLoS ONE, 2010
Phycoerythrin (PE), anti-CD3 (OKT-3) Pacific Blue (PB), anti-CD8 (RPA-T8) PE, anti-CD107a (H4A3) Alexa Fluor 647, anti-CD107b (H4B4) Alexa Fluor 647 (BD Biosciences, Erembodegem, Belgium), HLA-A2/MART-1 multimer-PE ...
Pyruvate kinase expression (PKM1 and PKM2) in cancer-associated fibroblasts drives stromal nutrient production and tumor growth
Lisanti Michael P. et al., In Cell Cycle, 2010
... anti-Cav-1 [#sc-894 (N-20); Santa Cruz Biotech], anti-Beclin1 (for immuno-blot #NBP1–00085, Novus; for immunostaining #2026–1, Epitomics), anti-LAMP1 [#sc-17768 (E-5); Santa Cruz Biotech], anti-BNIP-3 (#ab10433; Abcam), anti-Cathepsin B (#sc-13985 (FL-339); Santa ...
Discovery of a 1,5 dihydrobenzo (b)(1) diazepine-2,4-dione series of inhibitors of HIV-1 capsid assembly.
Kaufmann Gunnar F., In PLoS ONE, 2010
... Antibodies were obtained from commercial sources: anti-GST (Sigma–Aldrich), anti-core (MA1-080) (Thermo Scientific), anti-NS3 [H23] (Ab138830-Abcam), anti-LAMP1 (ab-24170-Abcam), horseradish peroxidase (HRP)-conjugated secondary ...
The immunostimulatory activity of unmethylated and methylated CpG oligodeoxynucleotide is dependent on their ability to colocalize with TLR9 in late endosomes
Cullis Pieter R et al., In Molecular Therapy, 2009
... another set of cell-containing glass slides were costained with EEA1 and goat anti-Lysosomal-Associated Membrane Protein 1 (LAMP1, Santa Cruz Biotechnology).
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Papers on LAMP-1
Dendritic Cell Immunotherapy for HIV-1 Infection Using Autologous HIV-1 RNA: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Nicolette et al., Montréal, Canada. In J Acquir Immune Defic Syndr, Feb 2016
When IFN-γ, IL-2, TNF-α, CD107a, and granzyme b expression was measured by multicolor flow cytometry, a greater percentage of AGS-004 than of placebo recipients had multifunctional CTL responses induced in the CD28+/CD45RA- CD8 effector/memory T-cell population to DCs electroporated with autologous antigens.
A critical role of LAMP-1 in avian reovirus P10 degradation associated with inhibition of apoptosis and virus release.
Zheng et al., Beijing, China. In Arch Virol, Feb 2016
We report here the identification of cellular lysosome-associated membrane protein 1 (LAMP-1) as an interaction partner of p10 by yeast two-hybrid screening, immunoprecipitation and confocal microscopy assays.
HIV-Specific CD8+ T Cell-Mediated Viral Suppression Correlates With the Expression of CD57.
Karlsson et al., Copenhagen, Denmark. In J Acquir Immune Defic Syndr, Feb 2016
The CD107a, interferon-γ, interleukin-2, tumor necrosis factor-α (TNF-α), and macrophage inflammatory protein-1β (MIP-1β) responses to HIV-1 were evaluated by intracellular staining.
Cytotoxic polyfunctionality maturation of cytomegalovirus-pp65-specific CD4 + and CD8 + T-cell responses in older adults positively correlates with response size.
Wang et al., Hopkins, United States. In Sci Rep, Dec 2015
In the current study, we examined the in vitro CMV-pp65-reactive T-cell response by comprehensively studying five effector functions (i.e., interleukin-2, tumor necrosis factor-α, interferon-γ, perforin, and CD107a expression) in 76 seropositive individuals aged 70 years or older.
A potent betulinic acid analogue ascertains an antagonistic mechanism between autophagy and proteasomal degradation pathway in HT-29 cells.
Das et al., Calcutta, India. In Bmc Cancer, Dec 2015
Furthermore we found the formation of autophagolysosome by colocalization of LAMP-1 with LC3B, LC3B with Lysosome, p62 with lysosome.
The diversity of platelet microparticles.
Brisson et al., Québec, Canada. In Curr Opin Hematol, Sep 2015
Circulating microparticles originating from megakaryocytes are distinguished from those derived from activated platelets by the presence of CD62P, LAMP-1, and immunoreceptor-based activation motif receptors.
Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins.
Green et al., Memphis, United States. In Nat Cell Biol, Jul 2015
Both PtdIns(3)P and reactive oxygen species are required for conjugation of LC3 to LAPosomes and subsequent association with LAMP1(+) lysosomes.
Emerging intracellular receptors for hemorrhagic fever viruses.
Brummelkamp et al., Amsterdam, Netherlands. In Trends Microbiol, Jul 2015
Recent screens for host factors identified such internal receptors for both viruses: Niemann-Pick disease type C1 protein (NPC1) for Ebola virus and lysosome-associated membrane protein 1 (LAMP1) for Lassa virus.
Take the tube: remodelling of the endosomal system by intracellular Salmonella enterica.
Hensel et al., Osnabrück, Germany. In Cell Microbiol, May 2015
For example, one kind of SIT, the LAMP1-positive Salmonella-induced filaments (SIF), are composed of double-membrane tubules, with an inner lumen containing host cell cytosol and cytoskeletal filaments, and an outer lumen containing endocytosed cargo.
Lysosome and Cytoskeleton Pathways Are Robustly Enriched in the Blood of Septic Patients: A Meta-Analysis of Transcriptomic Data.
Gao et al., Baltimore, United States. In Mediators Inflamm, 2014
The key regulatory genes in the "Lysosome" pathway include lysosomal acid hydrolases (e.g., protease cathepsin A, D) as well as the major (LAMP1, 2) and minor (SORT1, LAPTM4B) membrane proteins.
Virus entry. Lassa virus entry requires a trigger-induced receptor switch.
Brummelkamp et al., Amsterdam, Netherlands. In Science, 2014
We found that Lassa virus readily engaged its cell-surface receptor α-dystroglycan in avian cells, but virus entry in susceptible species involved a pH-dependent switch to an intracellular receptor, the lysosome-resident protein LAMP1.
Autophagy-dependent ATP release from dying cells via lysosomal exocytosis.
Kroemer et al., Villejuif, France. In Autophagy, 2013
In addition, we found that ATP release in this setting is mediated by a molecular mechanism that involves lysosomal-associated membrane protein 1 (LAMP1)- and pannexin 1 (PANX1)-dependent lysosomal exocytosis.
Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism.
Baumgartner et al., Zürich, Switzerland. In Nat Genet, 2012
Our results show that ABCD4 colocalizes with the lysosomal proteins LAMP1 and LMBD1, the latter of which is deficient in the cblF defect.
Salmonella acquires lysosome-associated membrane protein 1 (LAMP1) on phagosomes from Golgi via SipC protein-mediated recruitment of host Syntaxin6.
Mukhopadhyay et al., New Delhi, India. In J Biol Chem, 2012
a novel mechanism showing how Salmonella acquires LAMP1 through a SipC-Syntaxin6-mediated interaction probably to stabilize their niche in macrophages
Expression of NKG2D and CD107 in CD8(+) effector memory lymphocytes in Churg-Strauss syndrome.
Guida et al., Torino, Italy. In Clin Exp Rheumatol, 2012
Report expression of NKG2D and CD107 in CD8(+) effector memory lymphocytes in Churg-Strauss syndrome.
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors.
Zitvogel et al., Villejuif, France. In Nat Med, 2011
In a retrospective analysis of 80 individuals with GIST, predominant expression of the immunosuppressive NKp30c isoform (over the immunostimulatory NKp30a and NKp30b isoforms) was associated with reduced survival of subjects, decreased NKp30-dependent tumor necrosis factor-α (TNF-α) and CD107a release, and defective interferon-γ (IFN-γ) and interleukin-12 (IL-12) secretion in the NK-DC cross-talk that could be restored by blocking of IL-10.
Kinetic evidence that newly-synthesized endogenous lysosome-associated membrane protein-1 (LAMP-1) first transits early endosomes before it is delivered to lysosomes.
Thilo et al., Cape Town, South Africa. In Mol Membr Biol, 2011
The kinetic observations provide sufficient quantitative evidence that in P338D(1) cells the bulk of newly-synthesized endogenous LAMP-1 first appeared in early endosomes, before it was delivered to late endosomes and lysosomes about 25 min later.
Effects of human full-length amelogenin on the proliferation of human mesenchymal stem cells derived from bone marrow.
Tanne et al., Hiroshima, Japan. In Cell Tissue Res, 2010
Human full-length amelogenin increases the proliferation of mesenchymal stem cells by interaction with LAMP1 through the MAPK-ERK signaling pathway.
Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis.
Charbit et al., Paris, France. In Plos One, 2009
nucleolin and LAMP-1 have a role in promoting infection of human monocytes by Francisella tularensis
Integrin-dependent organization and bidirectional vesicular traffic at cytotoxic immune synapses.
Long et al., Rockville, United States. In Immunity, 2009
Lysosomal protein LAMP-1 that was exocytosed during degranulation accumulated in a large and spatially stable cluster, which overlapped with a site of membrane internalization.
More papers using LAMP-1 antibodies
Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation.
Gay Nick, In PLoS ONE, 2009
... (Affinity Bioreagents), anti-calnexin pAb and anti-calreticulin pAb (Stressgen, Victoria, Canada), anti-p115 pAb (Calbiochem, Darmstadt, Germany), anti-LAMP-1 mAb (Biolegend), anti-MPR pAb (Abcam, Cambridge, ...
PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation.
Ramakrishnan Lalita, In PLoS Pathogens, 2008
... The ID4B rat monoclonal LAMP-1 antibody was from BD Biosciences (San Jose, CA) and ...
SMART 6: recent updates and new developments.
Wong Nai Sum, In PLoS ONE, 2008
... For confocal imaging: Mouse monoclonal [H4A3] to Lamp1 (Abcam), rat anti-mouse Lamp1 ...
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
Hill Adrian VS et al., In Molecular Therapy, 2008
... for 5 hours in the presence of 1 µg/ml Pb9, 1 µl/ml Golgi-Plug, and 1 µl/ml Golgi-Stop (BD) and anti-CD107a PE (clone 1D4B) (eBioscience) at a final dilution of ...
Hrs and SNX3 functions in sorting and membrane invagination within multivesicular bodies.
Rappoport Joshua Z., In PLoS ONE, 2007
... Plymouth Meeting, PA), mouse monoclonal anti-EEA1 (BD Biosciences, Franklin Lakes, NJ), mouse monoclonal anti-human LAMP1 (CD107a; BD Biosciences) and rabbit polyclonal anti-human ...
Mitochondrial membrane permeabilization in cell death.
Blanke Steven R., In PLoS Pathogens, 2006
... Cover; e) mouse monoclonal anti-LAMP1, from BD Biosciences (San Jose, CA); f) ...
A guided tour into subcellular colocalization analysis in light microscopy.
II Roy Martin Roop, In PLoS ONE, 2005
... Polyclonal antibodies (Abs) used were: anti-LVS (Becton Dickinson), anti-nucleolin, anti-calnexin, anti-actin, anti-histone H1 and anti-LAMP1 (Abcam); monoclonal antibodies (MoAbs) were ...
A guided tour into subcellular colocalization analysis in light microscopy
Multhoff Gabriele, In PLoS ONE, 2005
... The rat anti-Tubulin monoclonal, mouse anti-EEA1 monoclonal, and mouse anti-LAMP-1 monoclonal antibodies were from Abcam Coporation ...
Early endosomes associated with dynamic F-actin structures are required for late trafficking of H. pylori VacA toxin
Boquet Patrice et al., In The Journal of Cell Biology, 2004
... Anti-EEA1 and -LAMP1 mAbs were purchased from BD Biosciences.
ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages
Tall Alan R. et al., In The Journal of Cell Biology, 2003
... Rat anti–mouse monoclonal antibody (clone 1D4B) against LAMP1 was obtained from BD Biosciences.
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
Alessi Dario R. et al., In The Journal of Cell Biology, 2002
... The clathrin antibody was purchased from Abcam, the EEA1 and LAMP1 antibodies (raised in mouse) were purchased from BD Biosciences, and the Hrs antibody ...
Mycobacterium tuberculosis-specific CD8+ T cells preferentially recognize heavily infected cells.
Flynn JoAnne L., In PLoS Pathogens, 2002
... The following antibodies were used for flow cytometry: TAP1, TAP2, EEA-1, rab5, GM130, HLA-A2, LAMP-1-PE (BD Biosciences), PDI, KDEL, calreticulin (Stressgen), ...
YSK1 is activated by the Golgi matrix protein GM130 and plays a role in cell migration through its substrate 14-3-3ζ
Barr Francis A. et al., In The Journal of Cell Biology, 2002
... Mouse monoclonal anti-LAMP1/CD107a was purchased from Becton Dickinson.
Dissecting virus entry via endocytosis
Simons Kai L., In PLoS Biology, 2001
... ]; mouse monoclonal IgG anti-LAMP-1 (H4A3) was from Santa Cruz Biotechnology (Santa Cruz, California, United ...
PDGF-regulated rab4-dependent recycling of alphavbeta3 integrin from early endosomes is necessary for cell adhesion and spreading
Serini Guido et al., In Cell Research, 2000
... Mouse mAbs anti-Rac1 (102), anti-Rab5 (1/Rab5), and anti-LAMP1 (H4A3) were from BD Biosciences.
Neuron to glia signaling triggers myelin membrane exocytosis from endosomal storage sites
Simons Mikael et al., In The Journal of Cell Biology, 1999
... IgG; BD Transduction Laboratories), GFP (Synaptic Systems GmbH), caveolin-1 (monoclonal IgM; BD Biosciences), and Lamp-1 (CD107a, rat monoclonal; BD Biosciences).
CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis
Ghosh Sankar et al., In The Journal of Cell Biology, 1999
... BioReagents, Inc.), anti-EEA1 (BD Biosciences), anti-TGN38 (BD Biosciences), anti–mouse transferrin receptor (BD Biosciences; C2), anti–mouse LAMP1 (BD Biosciences; ID4B), and anti-GAPDH4 (Fitzgerald ...
T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function.
Sarkar Devanand, In PLoS ONE, 1998
... Fluorescent-conjugated mouse Abs: anti-CD49b, anti-CD11c, anti-CD69, anti-CD44, anti-perforin, anti-granzyme, anti-IL10, anti-IFNγ, anti EpCam and anti-CD107a were from eBioscience (San Diego, CA) and ...
Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers
Van Dyke Rebecca W, In BMC Physiology, 1998
... ] and LAMP1 from Santa Cruz Biotechnology (Santa Cruz, CA) were ...
The 39-kDa receptor-associated protein interacts with two members of the low density lipoprotein receptor family, alpha 2-macroglobulin receptor and glycoprotein 330.
Johannes Ludger, In PLoS ONE, 1991
... Following antibodies were used: monoclonal antibody against EEA1 and LAMP-1 (BD Biosciences), monoclonal antibody against G58K ...
A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR.
Lenz Laurel L., In PLoS ONE, 1987
... Monoclonal rat anti-LAMP-1 (ID4B) and rabbit anti-cyaA (3D1) were from BD-Biosciences and Santa Cruz Biotechnology, respectively ...
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