The diversity of platelet microparticles.
Québec, Canada. In Curr Opin Hematol, Sep 2015
Circulating microparticles originating from megakaryocytes are distinguished from those derived from activated platelets by the presence of CD62P, LAMP-1, and immunoreceptor-based activation motif receptors.
Emerging intracellular receptors for hemorrhagic fever viruses.
Amsterdam, Netherlands. In Trends Microbiol, Jul 2015
Recent screens for host factors identified such internal receptors for both viruses: Niemann-Pick disease type C1 protein (NPC1) for Ebola virus and lysosome-associated membrane protein 1 (LAMP1) for Lassa virus.
Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors.
More papers using
Villejuif, France. In Nat Med, 2011
In a retrospective analysis of 80 individuals with GIST, predominant expression of the immunosuppressive NKp30c isoform (over the immunostimulatory NKp30a and NKp30b isoforms) was associated with reduced survival of subjects, decreased NKp30-dependent tumor necrosis factor-α (TNF-α) and CD107a release, and defective interferon-γ (IFN-γ) and interleukin-12 (IL-12) secretion in the NK-DC cross-talk that could be restored by blocking of IL-10.
Identification of a polyI:C-inducible membrane protein that participates in dendritic cell-mediated natural killer cell activation.
In PLoS ONE, 2009
... (Affinity Bioreagents), anti-calnexin pAb and anti-calreticulin pAb (Stressgen, Victoria, Canada), anti-p115 pAb (Calbiochem, Darmstadt, Germany), anti-LAMP-1 mAb (Biolegend), anti-MPR pAb (Abcam, Cambridge, ... Mycobacterium tuberculosis-specific CD8+ T cells preferentially recognize heavily infected cells.
In PLoS Pathogens, 2002
... The following antibodies were used for flow cytometry: TAP1, TAP2, EEA-1, rab5, GM130, HLA-A2, LAMP-1-PE (BD Biosciences), PDI, KDEL, calreticulin (Stressgen), ... T cell-derived IL-10 promotes lung cancer growth by suppressing both T cell and APC function.
In PLoS ONE, 1998
... Fluorescent-conjugated mouse Abs: anti-CD49b, anti-CD11c, anti-CD69, anti-CD44, anti-perforin, anti-granzyme, anti-IL10, anti-IFNγ, anti EpCam and anti-CD107a were from eBioscience (San Diego, CA) and ...