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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 08 Dec 2016.

Laminin, beta 3

LAMB3
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq, Jul 2008] (from NCBI)
Papers on LAMB3
Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration.
GeneRIF
Miyazaki et al., Yokohama, Japan. In Plos One, 2011
Data show laminin-332 (alpha3ss3gamma2)(Lm332) matrix supported adhesion of keratinocytes much more strongly and stably than purified Lm332.
Aberrant up-regulation of LAMB3 and LAMC2 by promoter demethylation in gastric cancer.
GeneRIF
Kim et al., Taej┼Ćn, South Korea. In Biochem Biophys Res Commun, 2011
These results suggest that epigenetic activation of LAMB3 and LAMC2 may play an important role in gastric carcinogenesis.
Type XVII collagen (BP180) can function as a cell-matrix adhesion molecule via binding to laminin 332.
GeneRIF
Giudice et al., Milwaukee, United States. In Matrix Biol, 2011
Cell surface COL17 can interact with laminin 332 and, together, participate in the adherence of a cell to the extracellular matrix.
Polymorphisms involved in the miR-218-LAMB3 pathway and susceptibility of cervical cancer, a case-control study in Chinese women.
GeneRIF
Hu et al., Nanjing, China. In Gynecol Oncol, 2010
The LAMB3 rs2566 variant CT/TT genotypes were associated with a significantly increased risk of cervical cancer, compared with the wild type CC genotype.
Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility.
GeneRIF
Gu et al., Sendai, Japan. In J Biol Chem, 2010
Bisecting GlcNAc residues on laminin-332 down-regulate galectin-3-dependent keratinocyte motility.
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