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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Laminin, alpha 1

Lama, LAMA1, laminin alpha 1
Top mentioned proteins: CAN, BCR, ABL, ACID, HAD
Papers using Lama antibodies
Characterization of the ligand-binding specificities of integrin alpha3beta1 and alpha6beta1 using a panel of purified laminin isoforms containing distinct alpha chains.
Rojas Mauricio, In PLoS ONE, 2002
... (Kalinin B1) from Transduction Laboratories (Lexington, KY), rabbit polyclonal antibody against the laminin α5 chain (LAMA A01) from Abnova (Taipei, Taiwan), anti-fibronectin antibodies ...
Papers on Lama
Magnetic Resonance Imaging of Malformations of Midbrain-Hindbrain.
Castillo et al., Al Manşūrah, Egypt. In J Comput Assist Tomogr, Jan 2016
Cerebellar dysplasias are seen in Chudley-McCullough syndrome, associated with LAMA1 mutations and GPR56 mutations; Lhermitte-Duclos disease; and focal cerebellar dysplasias.
Enteractinococcus lamae sp. nov. and Enteractinococcus viverrae sp. nov., isolated from animal faeces.
Huang et al., Shenyang, China. In Antonie Van Leeuwenhoek, Dec 2015
Two novel actinobacteria, designated strains YIM 101617(T) and YIM 101632(T), were isolated from Lama pacos (alpaca) and Viverra zibetha (civet) faeces in Yunnan Wild Animal Park in Yunnan province, southwestern China.
Oestrogen and Progesterone Receptors and COX-2 Expression in Endometrial Biopsy Samples During Maternal Recognition of Pregnancy in Llamas (Lama glama).
Aba et al., Tandil, Argentina. In Reprod Domest Anim, Dec 2015
Endometrial expression of oestrogen receptor-α (ERα), progesterone receptor (PR) and cyclooxigenase-2 (COX-2) was evaluated in non-pregnant and pregnant llamas during the period when luteolysis/maternal recognition of pregnancy is expected to occur.
Interaction between corticosteroids and muscarinic antagonists in human airways.
Matera et al., Roma, Italy. In Pulm Pharmacol Ther, Dec 2015
The aim of this study was to pharmacologically investigate the interaction between the ICS beclomethasone and the LAMA glycopyrronium on the human airway smooth muscle (ASM) tone.
Dual bronchodilator therapy with aclidinium bromide/formoterol fumarate for chronic obstructive pulmonary disease.
Kerwin et al., Toronto, Canada. In Expert Rev Respir Med, Oct 2015
Results from clinical studies suggest that dual bronchodilator therapy with long-acting muscarinic receptor antagonists (LAMAs) and long-acting β2 adrenergic receptor agonists (LABAs) may provide additional benefit over LAMA or LABA monotherapy without additive effects on safety and tolerability.
Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.
El Khattabi et al., Utrecht, Netherlands. In Febs J, Sep 2015
In the present study, we generated VHHs against BACE1 by active immunization of Lama glama with the recombinant BACE1 protein.
[DNA methylation in the promoter regions of the laminin family genes in normal and breast carcinoma tissues].
Strelnikov et al., Moscow, Russia. In Mol Biol (mosk), Jul 2015
Genes prone to abnormal methylation in breast carcinoma include LAMA1, LAMA2, LAMA3B, LAMA4, LAMB1, and LAMC3.
A Novel Mutation in Isoform 3 of the Plasma Membrane Ca2+ Pump Impairs Cellular Ca2+ Homeostasis in a Patient with Cerebellar Ataxia and Laminin Subunit 1α Mutations.
Carafoli et al., Padova, Italy. In J Biol Chem, Jul 2015
The patient also carries two missense mutations in LAMA1, encoding laminin subunit 1α.
Replication Study in a Japanese Population to Evaluate the Association between 10 SNP Loci, Identified in European Genome-Wide Association Studies, and Type 2 Diabetes.
Maeda et al., Yokohama, Japan. In Plos One, 2014
We also examined the association of 3 additional loci: CCND2 and GIPR, identified in sex-differentiated analyses, and LAMA1, which was shown to be associated with non-obese European type 2 diabetes.
Pharmacologic rationale underlying the therapeutic effects of tiotropium/olodaterol in COPD.
Maselli et al., Catanzaro, Italy. In Ther Clin Risk Manag, 2014
In particular, these therapeutic agents are mostly long-acting compounds utilized via inhalation, and include LAMA (long-acting muscarinic receptor antagonists) and LABA (long-acting β2-adrenoceptor agonists).
A re-evaluation of the role of inhaled corticosteroids in the management of patients with chronic obstructive pulmonary disease.
Price et al., Toronto, Canada. In Expert Opin Pharmacother, 2014
EXPERT OPINION: For patients with COPD who do not have ACOS, a LAMA/LABA combination may be an appropriate starting therapy, apart from those with mild disease who can be managed with a single long-acting bronchodilator.
The statement of the Polish Society of Allergology experts on the treatment of difficult-to-treat asthma.
Kupczyk et al., Łódź, Poland. In Pneumonol Alergol Pol, 2014
New treatment options for patients with asthma include: ultra-long-acting beta2-agonists, long-acting muscarine receptor antagonists (LAMA), monoclonal antibodies, and non-pharmacological interventions.
Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.
German CML Study Group et al., Mannheim, Germany. In Plos One, 2014
We investigated the influence of p210BCR-ABL breakpoint variants and imatinib treatment on expression and proteolytic activity of Separase as measured with a specific fluorogenic assay on CML cell lines (b2a2: KCL-22, BV-173; b3a2: K562, LAMA-84).
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform.
Achour et al., Utrecht, Netherlands. In Mabs, 2014
We therefore leveraged the publicly available HTG and WGS databases of Lama pacos and Camelus ferus to retrieve the germline repertoire of V genes using human IGV genes as reference.
Pharmacologic rationale, efficacy and safety of the fixed-dose co-formulation of indacaterol and glycopyrronium.
Gallelli et al., Catanzaro, Italy. In Multidiscip Respir Med, 2013
Inhaled long-acting bronchodilators, namely LABA (long-acting β2-adrenergic agonists) and LAMA (long-acting muscarinic receptor antagonists) are the mainstay of COPD treatment.
α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals.
Miyajima et al., Sapporo, Japan. In J Biol Chem, 2012
alpha1- and alpha5-containing laminins differentially regulate the sequential events to form epithelial tissues via beta1 integrin signals.
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
Cauchi et al., Exeter, United Kingdom. In Plos Genet, 2012
we report associations with the LAMA1 and HMG20A (not previously associated at genome-wide significance in Europeans) gene regions with type 2 diabetes risk
Absence of post-phosphoryl modification in dystroglycanopathy mouse models and wild-type tissues expressing non-laminin binding form of α-dystroglycan.
Toda et al., Kōbe, Japan. In J Biol Chem, 2012
-DG prepared from lung- or testis-derived cells lacks the post-phosphoryl moiety and shows little laminin a1 and a2 binding activity.
Laminin-α1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-κB transcription factors but also has adverse effects.
Jarrett et al., San Antonio, United States. In Am J Physiol Cell Physiol, 2012
Laminin-alpha1 LG4-5 domain binding to dystroglycan mediates muscle cell survival, growth, and the AP-1 and NF-kappaB transcription factors but also has adverse effects.
Functional role of laminin α1 chain during cerebellum development.
Bagnard et al., Strasbourg, France. In Cell Adh Migr, 2011
Our data show that the absence of Lama1 has an impact on the Bergmann glia scaffold that aberrantly develops.
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