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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ADP-ribosylation factor-like 4C

Lak, ARL7
ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: CAN, p16, ACID, STEP, ARL4
Papers on Lak
Posttraumatic growth, depression and posttraumatic stress in relation to quality of life in tsunami survivors: a longitudinal study.
Heir et al., Norway. In Health Qual Life Outcomes, 2014
METHODS: A total of 58 Norwegian adults who were present in Khao Lak, Thailand at the time of the 2004 Southeast Asia Tsunami completed self-report questionnaires 2 and 6 years after the disaster.
Re-evaluation of the species of hookworms infecting dogs in Central Vietnam.
Traub et al., Buôn Ma Thuột, Vietnam. In Parasit Vectors, 2014
METHODS: Faecal samples collected from 200 community dogs in Dak Lak province were subjected to faecal floatation for the detection of hookworm eggs.
The anti-proliferative and pro-apoptotic effects of the trans9, trans11 conjugated linoleic acid isomer on MCF-7 breast cancer cells are associated with LXR activation.
Nazih et al., Nantes, France. In Prostaglandins Leukot Essent Fatty Acids, 2013
t9,t11-CLA treatment led to an increase in the mRNA levels of LXR target genes involved in cholesterol efflux (ABCG1 and ARL7), as well as an increase of HMG-CoA-reductase which is the rate-limiting step of cholesterol biosynthesis.
MiR-26 controls LXR-dependent cholesterol efflux by targeting ABCA1 and ARL7.
Zhao et al., Hangzhou, China. In Febs Lett, 2012
Here, we describe that miR-26, an LXR-suppressed miRNA, inhibits the expression of the ATP-binding cassette transporter A1 (ABCA1) and ADP-ribosylation factor-like 7 (ARL7), two LXR target genes which play critical roles in cholesterol efflux.
Lymphocyte α-kinase is a gout-susceptible gene involved in monosodium urate monohydrate-induced inflammatory responses.
Ko et al., Kao-hsiung, Taiwan. In J Mol Med (berl), 2011
ALPK1 is a gout-susceptible gene involved in Monosodium urate monohydrate-induced inflammatory responses and may contribute to the development of gout by enhancing the inflammatory responses via the MAP kinase pathway
Constitutive activation of LXR in macrophages regulates metabolic and inflammatory gene expression: identification of ARL7 as a direct target.
Tontonoz et al., Los Angeles, United States. In J Lipid Res, 2011
an important role of LXRs in the coordinated regulation of lipid metabolic and inflammatory gene programs in macrophages
Motor coordination deficits in Alpk1 mutant mice with the inserted piggyBac transposon.
Xu et al., Shanghai, China. In Bmc Neurosci, 2010
Transposon-inserted Alpk1 homozygous mutant mice display severe defects in motor coordination in a series of behavioral analyses.
ADP-ribosylation factor like 7 (ARL7) interacts with alpha-tubulin and modulates intracellular vesicular transport.
Cai et al., Hangzhou, China. In Biochem Biophys Res Commun, 2009
ARL7 might modulate the intracellular vesicular transport via interaction with microtubules.
[Study on radiation sensitivity of colorectal cancer cells using gene expression profile].
Zhao et al., Suzhou, China. In Zhonghua Wei Chang Wai Ke Za Zhi, 2009
In Lovo cells, 908 up-regulated genes were found, including higher expression genes CEACAM5, THBS1, SERPINE2, ARL7, HPGD, while 1312 genes were down-regulated.
The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane.
Munro et al., Cambridge, United Kingdom. In Curr Biol, 2007
Study shows that three related Arf-like GTPases Arl4a, Arl4c, and Arl4d, are able to recruit ARNO and other cytohesins to the plasma membrane by binding to their PH domains irrespective of whether they are in the diglycine or triglycine form.
ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export.
Seedorf et al., Münster, Germany. In Febs Lett, 2004
Here, we identify ADP-ribosylation factor (ARF)-like 7 (ARL7) as the only ARF- and ARL-family member whose mRNA-expression is induced by liver X-receptor/retinoid X-receptor agonists or cholesterol loading in human macrophages.
Sucrose-induced vacuolation results in increased expression of cholesterol biosynthesis and lysosomal genes.
Thoene et al., New Orleans, United States. In Exp Cell Res, 2004
The lysosomal genes neuraminidase, CLN3, and CLCN5 and the small GTP-binding proteins Rab7L1 and Arl7 were also increased.
Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication.
Cherfils et al., Gif-sur-Yvette, France. In Embo Rep, 2002
Here we define the sequence and structural determinants that propagate information across the protein and identify them in all of the Arf family proteins other than Arl6 and Arl4/Arl7.
ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal.
Joost et al., Aachen, Germany. In Febs Lett, 1999
The novel ARF-like GTPase ARL7 is a close relative of ARL4 and ARL6 (71% and 59%) identical amino acids).
Effects of melatonin on estrogen receptor expression in the forebrain of outbred (Lak.LVG) golden hamsters.
Harlan et al., New Orleans, United States. In Brain Res, 1997
Since melatonin can modulate estrogen receptor (ER) expression in other tissues, immunocytochemical and ribonuclease protection analyses were used to examine the effects of 12 weeks of daily late afternoon injections of melatonin on ER protein and mRNA levels in the hypothalamus of Lak.LVG golden hamsters.
Influence of N-methyl-D-aspartate on the reproductive axis of male Syrian hamsters.
Collins et al., Beaverton, United States. In J Endocrinol, 1993
The influence of excitatory amino acids (EAAs) on reproductive neuroendocrine function was investigated in adult male Syrian hamsters of the LSH/Ss Lak strain.
Pathogenesis of a phleboviral infection (Punta Toro virus) in golden Syrian hamsters.
Peters et al., Frederick, United States. In Arch Virol, 1989
The Adames strain (eastern Panama) of PTV (LD50 approximately 1 PFU, sc) caused an acute fatal disease (average survival time, 3.8 days) in 10-week-old Lak: LVG (SYR) hamsters.
Similarities between LAK cells derived from human thymocytes and peripheral blood lymphocytes: expression of the NKH-1 and CD3 antigens.
Golub et al., In Cell Immunol, 1988
Human thymocytes are devoid of NK cells but develop lymphokine-activated killer (LAK) activity after culture with recombinant interleukin-2 (rIL-2).
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