Carbonyl stress phenomena during chronic infection with Opisthorchis felineus.
Tomsk, Russia. In Parasitol Int, Feb 2016
Expression of mRNA encoding glyoxalase 1 decreased at 8weeks of the infection and catalytic activity as well decreased at 8 and 12weeks after infection, and the expression of the glyoxalase 2 decreased until 36week post infection, which associated with the decreasing activity of the enzyme at 8, 12week post infection.
In Biomol Concepts, Jan 2016
The glyoxalase enzyme system utilizes intracellular thiols such as glutathione to convert α-ketoaldehydes, such as methylglyoxal, into D-hydroxyacids.
Methylglyoxal, the dark side of glycolysis.
Lausanne, Switzerland. In Front Neurosci, 2014
In normal situations, cells are protected against methylglyoxal toxicity by different mechanisms and in particular the glyoxalase system, which represents the most important pathway for the detoxification of methylglyoxal.