Impacts of climate change on distributions and diversity of ungulates on the Tibetan Plateau.
In Ecol Appl, 2015
We used three general circulation (MK3, HADCM3, MIROC3_2-MED) and three emissions scenarios (Bl, A1B, A2) to derive estimated future measurements of 14 environmental variables over three time periods (2020, 2050, 2080), and then modeled species distributions using these predicted environmental measurements for each time period under two dispersal hypotheses (full and zero, respectively).
The macrophage response towards LPS and its control through the p38(MAPK)-STAT3 axis.
Düsseldorf, Germany. In Cell Signal, 2012
In this context regulation of suppressor of cytokine signaling (SOCS)3 expression and the recently described divergent regulatory roles of the two p38(MAPK)-activated protein kinases MK2 and MK3 for the regulation of LPS-induced NF-κB- and IRF3-mediated signal-transduction and gene expression, which includes the regulation of IFNβ, IL-10 and DUSP1, appears to play an important role.
MAPKAP kinases - MKs - two's company, three's a crowd.
Hannover, Germany. In Nat Rev Mol Cell Biol, 2006
Downstream of mitogen-activated protein kinases (MAPKs), three structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) - MK2, MK3 and MK5 - signal to diverse cellular targets.