Keeping Wnt signalosome in check by vesicular traffic.
Newark, United States. In J Cell Physiol, Jun 2015
Updates are provided for the regulatory mechanisms related to the three critical cell surface complexes, Wnt-Fzd-LRP6, Dkk1-Kremen-LRP6, and R-spondin-LGR5-RNF43, which potently influence Wnt signaling.
Role of wingless tail signaling pathway in osteoporosis: an update of current knowledge.
Thessaloníki, Greece. In Curr Opin Endocrinol Diabetes Obes, 2011
RECENT FINDINGS: New insights into the mechanisms regulating Wnt/β-catenin canonical pathway, including the role of Kremen-2 receptor, lamin A/C protein, periostin, and pleiotropin in bone physiology, the crosstalk between the RUNX-2 transcription-factor cascade and the Wnt pathway, and the concept that individual Wnt ligands may have a unique and distinct mission in bone milieu, are presented.