Inactivation of C4orf26 in toothless placental mammals.
Riverside, United States. In Mol Phylogenet Evol, Dec 2015
UNASSIGNED: Previous studies have reported inactivated copies of six enamel-related genes (AMBN, AMEL, AMTN, ENAM, KLK4, MMP20) and one dentin-related gene (DSPP) in one or more toothless vertebrates and/or vertebrates with enamelless teeth, thereby providing evidence that these genes are enamel or tooth-specific with respect to their critical functions that are maintained by natural selection.
Amelogenesis imperfecta: an introduction.
In Br Dent J, 2012
Amelogenesis imperfecta (AI) is an inherited disorder that is associated with mutations in five genes (AMEL; ENAM; MMP20; KLK4 and FAM83H) with a wide range of clinical presentations (phenotypes).
Defining a new candidate gene for amelogenesis imperfecta: from molecular genetics to biochemistry.
Santiago, Chile. In Biochem Genet, 2011
These disorders are considered clinically and genetically heterogeneous in etiology, involving a variety of genes, such as AMELX, ENAM, DLX3, FAM83H, MMP-20, KLK4, and WDR72.