SPAK and OSR1 Sensitive Kir2.1 K+ Channels.
Tübingen, Germany. In Neurosignals, Jan 2016
BACKGROUND/AIMS: Kir2.1 (KCNJ2) channels are expressed in neurons, skeletal muscle and cardiac tissue and maintain the resting membrane potential.
Genetics of vasculitis.
Johannesburg, South Africa. In Curr Opin Rheumatol, 2015
These associations include ERAP1, CCR1-CCR3, STAT4, KLRC4, GIMAP4, and TNFAIP3 in Behçet's disease; BLK and CD40 in Kawasaki disease; SERPINA1 and SEMA6A in antineutrophil cytoplasmic antibody associated vasculitides; IL12B and FCGR2A/ FCGR2A in Takayasu arteritis; and CECR1 in a newly defined vascular inflammatory syndrome associated with adenosine deaminase (ADA2) deficiency.
The role of dasatinib in the management of chronic myeloid leukemia.
Nanjing, China. In Drug Des Devel Ther, 2014
It potently inhibits BCR/ABL and SRC-family kinases (SRC, LCK, HCK, YES, FYN, FGR, BLK, LYN, FRK), as well as c-KIT, PDGFR-a and -b, and ephrin receptor kinase.