The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.
Ann Arbor, United States. In J Cell Sci, Apr 2015
To examine a role for the heterotrimeric KIF3A-KIF3B-KAP3 kinesin-2 motor complex in regulating GLI activity, we performed a series of structure-function analyses using biochemical, cell signaling and in vivo approaches that define novel specific interactions between GLI proteins and two components of this complex, KAP3 and KIF3A.
Targeting of p0071 to the midbody depends on KIF3.
Halle, Germany. In J Cell Sci, 2009
Data indicate that p0071 and Ect2 are transported via distinct motors and identify a novel pathway implicating KIF3 in the regulation of actin organization during cytokinesis