MiR-486 Regulates Cholesterol Efflux by Targeting HAT1.
Hengyang, China. In Biochem Biophys Res Commun, Jan 2016
METHODS AND RESULTS: Based on bioinformatics analysis and luciferase reporter assay, we transfected miR-486 mimic and miR-486 inhibitor into THP-1 macrophage-derived foam cells, and found that miR-486 directly bound to histone acetyltransferase-1 (HAT1) 3'UTR, and downregulated its mRNA and protein expression.
Histone acetyltransferase 1: more than just an enzyme?
Columbus, United States. In Biochim Biophys Acta, 2013
Histone acetyltransferase 1 (HAT1) is an enzyme that is likely to be responsible for the acetylation that occurs on lysines 5 and 12 of the NH2-terminal tail of newly synthesized histone H4.
Ion channels in plants.
Würzburg, Germany. In Physiol Rev, 2012
Interestingly, one of the first identified potassium-channel genes encoding the Shaker-type channel KAT1 was shown to be highly expressed in guard cells.
Abscisic acid signal off the STARting block.
Gif-sur-Yvette, France. In Mol Plant, 2011
thus unleashing the pathway by freeing them to phosphorylate downstream targets that now include several b-ZIP transcription factors, ion channels (SLAC1, KAT1), and a NADPH oxidase (AtrbohF).
Endocytotic cycling of PM proteins.
West Lafayette, United States. In Annu Rev Plant Biol, 2004
Recent evidence of plasma membrane cycling of members of the PIN auxin efflux facilitator family and the KAT1 inwardly rectifying potassium channel demonstrates that endocytotic cycling of some form occurs in plants.