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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

NFKB inhibitor interacting Ras-like 1

kappaB-Ras, kappaB-Ras1, KBRAS1, IkappaB-interacting Ras-like protein-1
Top mentioned proteins: NF-kappaB, KBRAS2, IkappaBbeta, p65, IkappaBalpha
Papers on kappaB-Ras
Prognostic significance of kappaB-Ras1 expression in gliomas.
GeneRIF
Cheng et al., Xi'an, China. In Med Oncol, 2012
Low kappaB-Ras1 expression is associated with gliomas.
KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.
Itoh et al., Ikoma, Japan. In J Biol Chem, 2010
NF-κB is an important transcription factor involved in various biological responses, including inflammation, cell differentiation, and tumorigenesis.
Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas.
GeneRIF
Kashuba et al., Kiev, Ukraine. In Exp Oncol, 2010
It was shown the decreased expression level of NKIRAS1 in Renal cell carcinoma
Genetic variation in the nuclear factor kappaB pathway in relation to susceptibility to rheumatoid arthritis.
Gonzalez et al., Santiago de Compostela, Spain. In Ann Rheum Dis, 2009
A total of 181 single nucleotide polymorphisms (SNPs) uniformly spaced along the genomic sequences of 17 core genes of the NFkappaB pathway (REL, RELA, RELB, NFKB1, NFKB2, NFKBIA, NFKBIB, NFKBIE, IKBKA, IKBKB, IKBKE, IKBKAP, KBRAS1, KBRAS2, MAP3K1, MAP3K14, TAX1BP1) were studied by mass spectrometry analysis complemented with 5'-nuclease fluorescence assays in the discovery set, 458 patients with RA and 657 controls.
FOXO3a turns the tumor necrosis factor receptor signaling towards apoptosis through reciprocal regulation of c-Jun N-terminal kinase and NF-kappaB.
Kim et al., Seoul, South Korea. In Arterioscler Thromb Vasc Biol, 2008
Furthermore, kappaB-Ras1 (IkappaB-interacting Ras-like protein-1) which is known to block IkappaB degradation was found increased, and intranuclear translocation of NF-kappaB was inhibited.
Inhibition of transcription factor NF-kappaB activation by kappaB-Ras.
Ghosh et al., San Diego, United States. In Methods Enzymol, 2005
kappaB-Ras1 and kappaB-Ras2 are two small proteins that display similarity at the amino acid level to Ras-like small GTPases.
Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras.
Ghosh et al., San Diego, United States. In Mol Cell Biol, 2004
We show here that IkappaBbeta exists in at least two different forms: one that is bound to the NF-kappaB dimer and the other bound to both NF-kappaB and kappaB-Ras, a Ras-like small G protein.
KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes.
Ghosh et al., San Diego, United States. In J Biol Chem, 2003
A small Ras-like G-protein, kappaB-Ras, participates with the IkappaBbeta insert to effectively mask the NF-kappaB nuclear localization potential.
A subclass of Ras proteins that regulate the degradation of IkappaB.
Impact
Ghosh et al., New Haven, United States. In Science, 2000
These proteins, kappaB-Ras1 and kappaB-Ras2, interact with the PEST domains of IkappaBalpha and IkappaBbeta [inhibitors of the transcription factor nuclear factor kappa B (NF-kappaB)] and decrease their rate of degradation.
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