Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study.
San Diego, United States. In Schizophr Res, Jan 2016
Genotyping via a custom array of 1536 SNPs from 94 candidate genes identified associations for CTNNA2, ERBB4, GRID1, GRID2, GRIK3, GRIK4, GRIN2B, NOS1AP, NRG1, and RELN across multiple endophenotypes.
Regulation of protein kinases by lipids.
Bethesda, United States. In Curr Opin Struct Biol, 2011
Recent structural studies have identified a new membrane association domain, the Kinase Associated 1 (KA1) domain, which targets a number of yeast and mammalian protein kinases to membranes containing acidic phospholipids.
Kinases charging to the membrane.
Cambridge, United Kingdom. In Cell, 2011
In this issue, Moravcevic and colleagues (2010) survey membrane-interacting proteins in yeast and discover a new membrane-targeting module, the kinase associated-1 domain KA1, which ensures that proteins are active at the correct place and time.
The genetics of bipolar disorder.
Boston, United States. In Neuroscience, 2009
Several of these genes have been associated with the disorder in independent studies (including BDNF, DAOA, DISC1, GRIK4, SLC6A4, and TPH2), but none has been established.