Aggressive Periodontitis: microbes and host response, who to blame?
London, United Kingdom. In Virulence, 2014
Ensuing years of research have led to linkage analysis identification of specific genetic defects responsible for AgP in some families and to the finding that subgingival detection of A. actinomycet-emcomitans JP2 clone is a predictive factor for disease onset and progression.
Microbiology of aggressive periodontitis.
In Periodontol 2000, 2014
Its specific JP2 clone, however, shows properties of a true exogenous pathogen and has an important role in the development of aggressive periodontitis in certain populations.
Microarchitecture of the dyad.
Vancouver, Canada. In Cardiovasc Res, 2013
The essential role of proteins, such as junctophilin-2, calsequestrin, triadin, and junctin that maintain both the functional and structural integrity of the dyad have recently been elucidated giving a new mechanistic understanding of heart diseases, such as arrhythmias, hypertension, failure, and sudden cardiac death.