Leptin signalling pathways in hypothalamic neurons.
Seoul, South Korea. In Cell Mol Life Sci, Feb 2016
These include SOCS3, tyrosine phosphatase PTP1B, and inflammatory signaling pathways such as IKK-NFκB and JNK signaling, and ER stress-mitochondrial signaling.
Netrin-1 prevents the development of cardiac hypertrophy and heart failure.
Lanzhou, China. In Mol Med Report, Feb 2016
Furthermore, analysis of the signaling events indicated that netrin‑1‑mediated protection against cardiac hypertrophy was attributed to interruption of the activation of mitogen‑activated protein kinase kinase (MEK) kinase‑1 (K1)‑dependent MEK‑extracellular signal‑regulated protein kinase 1/2 (ERK1/2) and c‑Jun N‑terminal kinase 1/2 (JNK1/2).
FGF signalling regulates bone growth through autophagy.
More papers using
Pozzuoli, Italy. In Nature, Jan 2016
Surprisingly, post-natal induction of chondrocyte autophagy is mediated by the growth factor FGF18 through FGFR4 and JNK-dependent activation of the autophagy initiation complex VPS34-beclin-1.
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes.
In PLoS ONE, 2007
... antibody, anti-mouse monoclonal IgG peroxidase conjugate antibody, anti-β-actin polyclonal antibody, anti-ERK, p-ERK, p-p38, p38, JNK, p-JNK antibodies, and anti-mouse GHSR antibody were purchased from Santa Cruz Biotechnology Inc (Waltham, MA, USA) ... TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo
In The American Journal of Pathology, 2004
... (ab29379; Abcam, Cambridge, UK), phospho-SMAD3 (ab52903; Abcam), IKKβ (2370; Cell Signaling), phospho-IKKα/β (2681; Cell Signaling), JNK-1/2 (9252; Cell Signaling), phospho-JNK-1/2 (4668; Cell Signaling), ... In vivo identification of lymphocyte subsets exhibiting transcriptionally active NF-kappaB/Rel complexes.
In PLoS Pathogens, 1999
... MEK-2 (9125), p38-MAPK (9212), phospho-p38-MAPK (p38pT180-Y182, 9211), ERK (9102), phospho-ERK (ERKpT202-Y204, 9101), JNK (9252) and phospho-JNK (JNKpT183-Y185, 4668) and PD98059 were from Cell Signaling (Danvers, USA) ... Suppression of an absolute defect in type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in Neisseria gonorrhoeae
In PLoS Biology, 1997
... (Ser63), P44/42 MAPK, phospho-p44/42 MAPK (Thr202/Tyr204), phospho-MAPKAPK2 (Thr334), p38 MAPK, phospho-p38 MAPK (Thr108/Tyr182), SAPK/JNK, and phospho-SAPK/JNK (Thr183/Tyr185) were purchased from Cell Signaling Technology (Beverly, Massachusetts, United ... Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes
In Cell Death & Disease, 1986
... antibody, anti-total ERK1/2 antibody, anti-phospho-ERK1/2(Thr180/Tyr182) antibody, anti-MEK1 antibody, anti-MEK2 antibody, anti-total p38MAPK antibody, anit-phospho-p38MAPK(Thr202/Tyr204) antibody, anti-phospho-JNK(Thr183/Tyr185) antibody, and anti-PARP antibody were from Cell Signaling Technology (San Jose, CA, ...