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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Integrin, beta 5

ITGB5, integrin beta 5
Top mentioned proteins: HAD, CAN, POLYMERASE, AGE, Integrin beta4
Papers on ITGB5
Integrin αVβ3 and αVβ5 are required for leukemia inhibitory factor-mediated the adhesion of trophoblast cells to the endometrial cells.
New
Ha et al., Yangsan, South Korea. In Biochem Biophys Res Commun, Jan 2016
Here we show that LIF significantly induced mRNA expression of ITGAV, ITGB3, and ITGB5 in endometrial cells, as evidenced by RT-PCR and qRT-PCR analysis.
Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasion.
New
Ridky et al., Philadelphia, United States. In J Cell Sci, Dec 2015
These phenotypes depend only on the binding partners of integrin-αv - integrin β5 and integrin β6 (also known as ITGB5 and ITGB6, respectively).
Kindlin 3 (FERMT3) is associated with unstable atherosclerotic plaques, anti-inflammatory type II macrophages and upregulation of beta-2 integrins in all major arterial beds.
New
Hytönen et al., Tampere, Finland. In Atherosclerosis, Sep 2015
The other integrins (ITGA1, ITGAV, ITGB3, ITGB5) were downregulated.
Association between polymorphisms of microRNA-binding sites in integrin genes and gastric cancer in Chinese Han population.
New
Wang et al., Chengdu, China. In Tumour Biol, Apr 2015
Five SNPs of the microRNA-binding sites in the 3' UTR region of integrin genes (rs1062484 C/T in ITGA3, rs17664 A/G in ITGA6, rs3809865 A/T in ITGB3, rs743554 C/T in ITGB4, and rs2675 A/C in ITGB5) were studied using high resolution melting (HRM) analysis in 1000 GC patients and 1000 unrelated controls.
Quantitative tandem mass-spectrometry of skin tissue reveals putative psoriatic arthritis biomarkers.
Chandran et al., Toronto, Canada. In Clin Proteomics, 2014
ITGB5 and POSTN were measured in serum samples from 33 PsA and 15 PsC patients, using enzyme-linked immunosorbent assays.
Cytochrome b5 reductase 2 suppresses tumor formation in nasopharyngeal carcinoma by attenuating angiogenesis.
Huang et al., Nanning, China. In Ai Zheng, 2014
RESULTS: In CYB5R2-transfected NPC cells, PCR assays revealed up-regulated mRNA levels of Fas cell surface death receptor (FAS), FBJ murine osteosarcoma viral oncogene homolog (FOS), phosphoinositide-3-kinase regulatory subunit 1 (PIK3R1), integrin beta 3 (ITGB3), metastasis suppressor 1 (MTSS1), interferon beta 1 (IFNB1), and cyclin-dependent kinase inhibitor 2A (CDKN2A) and down-regulated levels of integrin beta 5 (ITGB5), insulin-like growth factor 1 (IGF1), TEK tyrosine kinase (TEK), transforming growth factor beta receptor 1 (TGFBR1), and VEGF.
Differential DNA Methylation in Relation to Age and Health Risks of Obesity.
Martínez et al., Pamplona, Spain. In Int J Mol Sci, 2014
Moreover, statistically significant associations between BMI or mRNA levels and two HRO-related CpG sites located in GPR133 and ITGB5 are reported.
Exposure to zearalenone mycotoxin alters in vitro porcine intestinal epithelial cells by differential gene expression.
Burlacu et al., Romania. In Toxicol Lett, 2014
ZEA determined the over expression of ITGB5 gene, essential against the attachment and adhesion of ETEC to porcine jejunal cells and of TFF2 implicated in mucosal protection.
Combinatorial fibronectin and laminin signaling promote highly efficient cardiac differentiation of human embryonic stem cells.
McCloskey et al., Merced, United States. In Biores Open Access, 2014
Moreover, the LN receptor integrin β4 (ITGB4) and FN receptor integrin β5 (ITGB5) genes, jointly with increased phosphorylated focal adhension kinase and phosphorylated extracellular signal-regulated kinases (p-ERKs), were up-regulated over 13-fold in H7 and H9 cultured on 70:30 FN:LN compared with gelatin.
Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology.
de Vernejoul et al., Paris, France. In Lab Invest, 2014
Although two of them have previously been found to be expressed in osteoclasts (ITGB5 and SERPINE2), the other five (CES1 (carboxyl esterase 1), UCHL1 (ubiquitin carboxy-terminal esterase L1, also known as ubiquitin thiolesterase), WARS (tryptophanyl-tRNA synthetase), GBP4 (guanylate-binding protein 4), and PRF1) are not yet known to have a role in this cell type.
ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells.
Baldus et al., Berlin, Germany. In Oncotarget, 2014
Genes significantly over-expressed after ERG induction strongly resembled adhesive mesenchymal-like genes that included integrins (ITGA10, ITGB5, ITGB3, ITGA2B), CD44, and CD24.
Association between polymorphisms in the integrin gene predicted microRNA binding sites and bladder cancer risk.
Zhang et al., Chengdu, China. In Int J Clin Exp Med, 2013
AC carriers of rs2675 in ITGB5 were associated with an increased risk of BC (OR 1.44, 95% CI 1.02-2.03).
Transforming growth factor-beta (TGF- β) signaling in paravertebral muscles in juvenile and adolescent idiopathic scoliosis.
Mazurek et al., Sosnowiec, Poland. In Biomed Res Int, 2013
Analysis of TGF-β responsive genes in the transcriptomes of patients with AIS suggested overrepresentation of the genes localized in the extracellular region of curve concavity: LTBP3, LTBP4, ITGB4, and ITGB5.
Transcriptome profiling of granulosa cells of bovine ovarian follicles during growth from small to large antral sizes.
Rodgers et al., Adelaide, Australia. In Bmc Genomics, 2013
The most important networks were associated with: (A) Notch, SLIT/ROBO and PI3K signalling, and (B) ITGB5 and extracellular matrix signalling through extracellular signal related kinases (ERKs).
RUNX2, GPX3 and PTX3 gene expression profiling in cumulus cells are reflective oocyte/embryo competence and potentially reliable predictors of embryo developmental competence in PCOS patients.
Liu et al., Yantai, China. In Reprod Biol Endocrinol, 2012
Seven genes (RUNX2, PSAT1, ADAMTS9, CXCL1, CXCL2, CXCL3, and ITGB5) were targeted from our previous cDNA microarray data which isolated genes related to oocyte nuclear maturation in PCOS patients.
Lack of integrin β5 in Merkel cell carcinomas and derived cell lines is frequently associated with Merkel cell polyomavirus positivity.
GeneRIF
Pfister et al., In J Dermatol Sci, 2012
Letter: loss of integrin beta5 in polyomavirus positive Merkel cell carcinoma may influence cell adhesion/migration.
Cross talk between engulfment receptors stabilin-2 and integrin αvβ5 orchestrates engulfment of phosphatidylserine-exposed erythrocytes.
GeneRIF
Kim et al., Taegu, South Korea. In Mol Cell Biol, 2012
knockdown of endogenous alphavbeta5 expression or treatment with a function-blocking alphavbeta5 antibody significantly decreased stabilin-2-mediated phagocytosis in the absence of soluble factors
Cyr61 induces IL-6 production by fibroblast-like synoviocytes promoting Th17 differentiation in rheumatoid arthritis.
GeneRIF
Li et al., Shanghai, China. In J Immunol, 2012
Cysteine-rich protein Cyr61 activates interleukin (IL)-6 production via the alphavbeta5/Akt/NF-kappaB signaling pathway in rheumatoid arthritis.
CCN3 increases cell motility and MMP-13 expression in human chondrosarcoma through integrin-dependent pathway.
GeneRIF
Tang et al., Taiwan. In J Cell Physiol, 2011
CCN3 enhances the migration of chondrosarcoma cells by increasing MMP-13 expression through the alphavbeta3/alphavbeta5 integrin receptor, FAK, PI3K, Akt, p65, and NF-kappaB signal transduction pathway.
Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells.
GeneRIF
Combs et al., Heidelberg, Germany. In Radiat Oncol, 2010
alphanubeta3 and alphanubeta5 have roles in photon-induced hypermigration of malignant glioma cells
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