Papers on
IRR
Alkaline pH sensor molecules.Maruyama et al., Okinawa, Japan. In J Neurosci Res, Nov 2015
Extracellular sensors include the receptor-type guanylyl cyclase, the insulin receptor-related receptor, ligand-gated Cl- channels, connexin hemichannels, two-pore-domain K+ channels, and transient receptor potential (TRP) channels.
Role of obinutuzumab in the treatment of chronic lymphocytic leukemia.Comeau et al., Shreveport, United States. In Am J Health Syst Pharm, Jul 2015
The main type of adverse effect reported in association with obinutuzumab use is infusion-related reactions (IRRs), which occurred in 66% of patients in the Phase III trial, with 20% of reactions categorized as grade 3 or 4; IRR risk can be reduced with appropriate dosing, premedication, patient monitoring, and immediate treatment of IRRs.
Insulin receptor-related receptor as an extracellular alkali sensor.Petrenko et al., Moscow, Russia. In Cell Metab, 2011
Disruption of insulin receptor-related receptor in mice impairs the renal response to alkali loading attested by development of metabolic alkalosis and decreased urinary bicarbonate excretion in response to this challenge
Grigg et al., Southampton, United Kingdom. In Unknown Journal, 0001
There was no difference in unscheduled medical attendances for wheezing episodes between children in the montelukast and placebo groups {mean 2.0 [standard deviation (SD) 2.6] vs. mean 2.3 (SD 2.7) unscheduled medical attendances; incidence rate ratio (IRR) 0.88, 95% confidence interval (CI) 0.77 to 1.01; p = 0.06}.