Rules of UGA-N decoding by near-cognate tRNAs and analysis of readthrough on short uORFs in yeast.
Praha, Czech Republic. In Rna, Feb 2016
UNASSIGNED: The molecular mechanism of stop codon recognition by the release factor eRF1 in complex with eRF3 has been described in great detail; however, our understanding of what determines the difference in termination efficiencies among various stop codon tetranucleotides and how near-cognate (nc) tRNAs recode stop codons during programmed readthrough in Saccharomyces cerevisiae is still poor.
Ethylene response factors in Arabidopsis immunity.
In J Exp Bot, Jan 2016
Notably, ethylene response factor (ERF) TFs are integrators of hormonal pathways and are directly responsible for the transcriptional regulation of several jasmonate (JA)/ethylene (ET)-responsive defence genes.
The catcher in the RIG-I.
Gießen, Germany. In Cytokine, Nov 2015
Activated RIG-I switches into a conformation that locks the ligand RNA and signals via the MAVS-IRF-3 axis, resulting in the upregulation of antiviral interferons.