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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.


Involucrin, a component of the keratinocyte crosslinked envelope, is found in the cytoplasm and crosslinked to membrane proteins by transglutaminase. This gene is mapped to 1q21, among calpactin I light chain, trichohyalin, profillaggrin, loricrin, and calcyclin. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: cytokeratin, Filaggrin, HAD, ACID, CAN
Papers using Involucrin antibodies
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair.
Imperiale Michael, In PLoS Pathogens, 2007
... Antibodies to GST(B-14), Nucleolin(C-23), E6AP(H-182), His(H-15), EGR-1(588), p300(N-15) Actin (I-19), Cytokeratin 10/13 (DE-K13) and Involucrin (SY8) were purchased from Santa Cruz Biotechnology; antibodies to AKT, phospho ...
Protection of neonates against pemphigus foliaceus by desmoglein 3
Stanley John R. et al., In The Journal of Cell Biology, 1999
... Construction and Genotyping of Involucrin-Dsg 3 Transgenic Mouse ...
Papers on Involucrin
Combination of low calcium with Y-27632 rock inhibitor increases the proliferative capacity, expansion potential and lifespan of primary human keratinocytes while retaining their capacity to differentiate into stratified epidermis in a 3D skin model.
Cowin et al., Australia. In Plos One, 2014
mRNA and protein was extracted and expression of differentiation markers Keratin 14 (K14), Keratin 10 (K10) and Involucrin (Inv) assessed by qRT-PCR and Western blotting.
Cytokeratin expression of engrafted three-dimensional culture tissues using epithelial cells derived from porcine periodontal ligaments.
Igarashi et al., Niigata, Japan. In J Oral Pathol Med, 2014
Involucrin was expressed in the certified layers in vitro at 14 days, but not in vivo.
Corticomedullary differentiation and maturational arrest in thymomas.
Marx et al., Göttingen, Germany. In Histopathology, 2014
Involucrin and cytokeratin 10 were used to study terminal mTEC maturation.
GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis.
Lamartine et al., Lyon, France. In Arch Dermatol Res, 2014
Moreover, GATA3 seems to be able to induce keratinocyte differentiation since its silencing leads to a decrease of both early and late differentiation markers such as Keratins 1 and 10, Involucrin and Loricrin.
Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility.
Watt et al., Cambridge, United Kingdom. In Elife, 2013
To test whether this influences tumour formation, we chemically induced tumours in EPI-/- mice, which lack three barrier proteins-Envoplakin, Periplakin, and Involucrin.
Maintenance of stem cell self-renewal in head and neck cancers requires actions of GSK3β influenced by CD44 and RHAMM.
Mackenzie et al., London, United Kingdom. In Stem Cells, 2013
GSK3β inhibition also reduces the expression of stem cell markers such as Oct4, Sox2, and Nanog and upregulates expression of the differentiation markers Calgranulin B and Involucrin in the CD44(high) /ESA(high) cell fraction.
Effects of Cervi cornus Colla (deer antler glue) in the reconstruction of a skin equivalent model.
Kim et al., Seoul, South Korea. In Arch Dermatol Res, 2013
Involucrin was obviously expressed in the upper layer of the epidermis in the HA and CCC model.
Effects of epidermal growth factor on the proliferation and cell cycle regulation of cultured human amnion epithelial cells.
Hayati et al., Kuala Lumpur, Malaysia. In J Biosci Bioeng, 2012
EGF also significantly decreased the pluripotent genes expression: Oct-3/4, Sox2 and Nanog; epithelial genes expression: CK14, p63, CK1 and Involucrin; and neuronal gene expression: NSE, NF-M and MAP 2. The results suggested that EGF is a strong mitogen that promotes the proliferation of HAECs through cell cycle regulation.
The effect of pimecrolimus on expression of genes associated with skin barrier dysfunction in atopic dermatitis skin lesions.
Jarzab et al., Katowice, Poland. In Exp Dermatol, 2012
Involucrin, a small proline-rich region (SPRR) 2C gene, and alternative pathway keratin 16 showed significant over-expression in lesional skin followed by significant decrease after PIM therapy.
Effects of human papillomavirus (HPV) type 16 oncoproteins on the expression of involucrin in human keratinocytes.
Veress et al., Debrecen, Hungary. In Virol J, 2011
The authors found that HPV 16 E6 but not E7 repressed IVL promoter activity in proliferating human foreskin keratinocyte cells.
Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.
Galloway et al., Seattle, United States. In Plos Pathog, 2011
Finally, we demonstrate that the decreased p300 protein levels concomitantly affect downstream signaling events, such as the expression of differentiation markers K1, K10 and Involucrin.
Involucrin, but not filaggrin and Kdap mRNA, expression is downregulated in 3-D cultures of intact rat hair bulbs after calcium stimulation.
Moskalewski et al., Warsaw, Poland. In Folia Histochem Cytobiol, 2010
The level of mRNA for differentiation markers: involucrin, filaggrin, keratinocyte differentiation associated protein and trichohyalin, was studied by RealTime PCR.
Coordinate interaction between IL-13 and epithelial differentiation cluster genes in eosinophilic esophagitis.
Rothenberg et al., Cincinnati, United States. In J Immunol, 2010
expression of the epidermal differentiation complex genes filaggrin and involucrin was strongly decreased directly by IL-13.
Involucrin-claudin-6 tail deletion mutant (CDelta206) transgenic mice: a model of delayed epidermal permeability barrier formation and repair.
Turksen et al., Ottawa, Canada. In Dis Model Mech, 2010
The Inv-Cldn6-CDelta206 transgenic mice displayed a developmental delay in epidermal permeability barrier formation, as shown by the expression of keratins and Cldns, and by X-Gal penetration assays.
[Blocking of Notch signaling decreased scar formation in rabbit ear hypertrophic scar model].
Xia et al., Xi'an, China. In Zhonghua Yi Xue Za Zhi, 2009
The expression of epidermal differentiation markers-keratin 14 (K14), keratin 19 (K19), Involucrin and Notch downstream molecules-P21, P63 were examined and analyzed with immunohistochemistry staining.
Dermatitis and aging-related barrier dysfunction in transgenic mice overexpressing an epidermal-targeted claudin 6 tail deletion mutant.
Turksen et al., Ottawa, Canada. In Plos One, 2008
the normally robust injury response mechanism of the epidermis is lost in the aging Involucrin-Cldn6-CDelta196 transgenic epidermis
[Preliminary study on biological characteristics of CD(44)(+) stem cells in human laryngeal carcinoma].
Xu et al., Changchun, China. In Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi, 2008
CD(44)(+) and CD(44)(-) cells were compared in their functional status (mRNA), cell cycles (G0/G1), their degree of differentiation (CK14 and Involucrin expression) and their morphologic character of the clone.
Cytokeratin changes in cell culture systems of epithelial cells isolated from oral mucosa: a short review.
Fonzi et al., Siena, Italy. In Ital J Anat Embryol, 2005
In the present paper, we examine phenotypic changes, development of suprabasal layer, and Involucrin expression occurring in differentiating oral epithelial cells, based on literature review and original data.
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