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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ALPI alkaline phosphatase, intestinal

intestinal alkaline phosphatase
Top mentioned proteins: ACID, HAD, CAN, V1a, AGE
Papers on intestinal alkaline phosphatase
Effects of enzymatic dephosphorylation on infant in vitro gastrointestinal digestibility of milk protein concentrate.
Zhou et al., Wuxi, China. In Food Chem, May 2016
A series of milk protein concentrate with 0-69% dephosphorylation were obtained by incubation with calf intestinal alkaline phosphatase at pH 6.5 for 0-420min.
Regulation of intestinal SGLT1 by catestatin in hyperleptinemic type 2 diabetic mice.
Rieg et al., San Diego, United States. In Lab Invest, Jan 2016
The alterations in architecture and SGLT1 abundance were not accompanied by changes in the localization of intestinal alkaline phosphatase, indicating intact differentiation.
Regulation of BmBDV NS1 by phosphorylation: Impact of mutagenesis at consensus phosphorylation sites on ATPase activity and cytopathic effects.
Yao et al., Zhenjiang, China. In J Invertebr Pathol, Jan 2016
After wild-type NS1 was treated with calf intestinal alkaline phosphatase (CIP), ATPase activity decreased significantly.
Oral antibodies to human intestinal alkaline phosphatase reduce dietary phytate phosphate bioavailability in the presence of dietary 1α-hydroxycholecalciferol.
Cook et al., Madison, United States. In Poult Sci, Jan 2016
UNASSIGNED: While it is well established that active vitamin D treatment increases dietary phytate phosphate utilization, the mechanism by which intestinal alkaline phosphatase (IAP) participates in phytate phosphate use is less clear.
Biodistribution and translational pharmacokinetic modeling of a human recombinant alkaline phosphatase.
Pickkers et al., Nijmegen, Netherlands. In Int J Pharm, Dec 2015
Clinical trials showed renal protective effects of bovine intestinal alkaline phosphatase (AP) in patients with sepsis-associated acute kidney injury (AKI).
Probiotic Pediococcus pentosaceus strain GS4 alleviates azoxymethane-induced toxicity in mice.
Khuda-Bukhsh et al., Vellore, India. In Nutr Res, Oct 2015
Probiotic GS4 intervention reduced the intestinal structural deformities as evident from the elevated brush border membrane-associated disaccharidases (sucrase, lactase) and intestinal alkaline phosphatase activities, which were found disrupted by AOM intoxication.
Effect of neonatal β3-adrenoceptor agonist CL 316,243 treatment on body fat accumulation and intestinal alkaline phosphatase activity in rats from reduced nests.
Raček et al., Košice, Slovakia. In Folia Histochem Cytobiol, 2014
Body composition was determined by magnetic resonance imaging, blood pressure was measured using non-invasive tail-cuff, and intestinal alkaline phosphatase (AP) activity was assessed by histochemistry.
Prostaglandin pathways in duodenal chemosensing.
Kaunitz et al., Los Angeles, United States. In J Gastroenterol Hepatol, 2014
Acid exposure augments purinergic ATP-P2Y signaling by inhibition of intestinal alkaline phosphatase activity.
Glucose Regulated Protein 78 Phosphorylation in Sperm Undergoes Dynamic Changes during Maturation.
Parte et al., Mumbai, India. In Plos One, 2014
Phosphatase assays using Calf intestinal alkaline phosphatase and Lambda protein phosphatase followed by nanofluidic proteomic immunoassay (NIA) show that in rat, GP4.96, GP4.94 and GP4.85 are the three phosphoforms in mature (caudal) sperm as against two phosphoforms GP4.96and GP4.94in immature (testicular) sperm.
Interplay between intestinal alkaline phosphatase, diet, gut microbes and immunity.
Gibson et al., Kelowna, Canada. In World J Gastroenterol, 2014
Intestinal alkaline phosphatase (IAP) plays an essential role in intestinal homeostasis and health through interactions with the resident microbiota, diet and the gut.
Intestinal alkaline phosphatase: novel functions and protective effects.
Lallès, France. In Nutr Rev, 2014
Important protective roles of intestinal alkaline phosphatase (IAP)--including regulation of intestinal surface pH, absorption of lipids, detoxification of free nucleotides and bacterial lipopolysaccharide, attenuation of intestinal inflammation, and possible modulation of the gut microbiota--have been reviewed recently.
Curcumin and chronic kidney disease (CKD): major mode of action through stimulating endogenous intestinal alkaline phosphatase.
Ghosh et al., Richmond, United States. In Molecules, 2013
This change in intestinal permeability is due to decreased expression of tight junction proteins and intestinal alkaline phosphatase (IAP).
Multisystemic functions of alkaline phosphatases.
Magne et al., Villeurbanne, France. In Methods Mol Biol, 2012
The brush border enzyme intestinal alkaline phosphatase (IAP) plays an important role in fatty acid (FA) absorption, in protecting gut barrier function, and in determining the composition of the gut microbiota via its ability to dephosphorylate lipopolysaccharide (LPS).
Prophylactic treatment with alkaline phosphatase in cardiac surgery induces endogenous alkaline phosphatase release.
Oeveren et al., Maastricht, Netherlands. In Int J Artif Organs, 2012
Intravenous bolus administration plus 8 hours continuous infusion of alkaline phosphatase in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass results in endogenous alkaline phosphatase release.
Identification of specific targets for the gut mucosal defense factor intestinal alkaline phosphatase.
Hodin et al., Boston, United States. In Am J Physiol Gastrointest Liver Physiol, 2010
Mechanism of IAP action appears to be through dephosphorylation of specific bacterial components, including LPS, CpG DNA, and flagellin, and not on live bacteria. IAP likely targets these bacterially derived molecules as gut mucosal defense factor.
Effect of metal ions on the secondary structure and activity of calf intestine phosphatase.
Zeng et al., Lanzhou, China. In Bmb Rep, 2008
Secondary structure of CIP after reaction with Co2+ in different conditions.
Distinct structure and activity recoveries reveal differences in metal binding between mammalian and Escherichia coli alkaline phosphatases.
Azzar et al., Villeurbanne, France. In Biochem J, 2006
differences in metal binding between bovine and Escherichia coli alkaline phosphatases
Benign familial hyperphosphatasemia.
Miller et al., Bethesda, United States. In Jama, 1989
Monoclonal antibodies to three alkaline phosphatase isoenzymes, intestinal, placental, and tissue nonspecific (liver/bone/kidney), demonstrated markedly increased intestinal alkaline phosphatase levels (29% to 44% of total) in all family members and significantly elevated liver/bone/kidney activity in the two offspring.
A monoclonal antibody that reacts with nonallelic enzyme glycoproteins.
Harris et al., In Science, 1982
One of six monoclonal antibodies raised against purified human placental alkaline phosphatase cross-reacts with the adult and fetal forms of intestinal alkaline phosphatase.
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