Cytokines make an indelible impression on neural stem cells.
Tallahassee, United States. In Cell Stem Cell, 07 Dec 2013
(2013) show that maternal exposure to the infection-induced inflammatory cytokine IL-6 produces lasting effects on forebrain stem cell pools of offspring during embryogenesis and throughout life.
Impact of Interleukin-6 in Hematological Malignancies.
Kiel, Germany. In Transfus Med Hemother, 31 Oct 2013
UNLABELLED: Almost 3 decades have passed since the discovery and cloning of IL-6, and a tremendous amount of work has contributed to the current knowledge of the biological functions of this cytokine, its receptor, and the signaling pathways that are activated.
Systemic iron homeostasis.
In Physiol Rev, 31 Oct 2013
Hepcidin and ferroportin also play a role in host defense and inflammation, and hepcidin synthesis is induced by inflammatory signals including interleukin-6 and activin B. This review summarizes and discusses recent progress in molecular characterization of systemic iron homeostasis and its disorders, and identifies areas for further investigation.
Obesity, Inflammation and Diet.
South Korea. In Pediatr Gastroenterol Hepatol Nutr, Sep 2013
Adipose tissue produces and releases a variety of adipokines (leptin, adiponectin, resistin, and visfatin), as well as pro- and anti-inflammatory cytokines (tumor necrosis factor-α, interleukin [IL]-4, IL-6, and others).
T Helper 17 Cells in Autoimmune Liver Diseases.
Japan. In Clin Dev Immunol, Dec 2012
Because the liver is known to be an important source of transforming growth factor- β and IL-6, which are cytokines that are crucial for Th17 differentiation, it is very likely that Th17 cells contribute to liver inflammation and autoimmunity.
Arzanol, a Potent mPGES-1 Inhibitor: Novel Anti-Inflammatory Agent.
More papers using
Mumbai, India. In Scientificworldjournal, Dec 2012
Arzanol has been reported to inhibit inflammatory transcription factor NF κ B activation, HIV replication in T cells, releases of IL-1 β , IL-6, IL-8, and TNF- α , and biosynthesis of PGE2 by potentially inhibiting mPGES-1 enzyme.
Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10–a role for IL-1 beta?
In Journal of Neuroinflammation, 2003
... Systems, Abingdon, UK), IL-6 and non-target (NT) siRNA (Invitrogen, Paisley, UK), recombinant IL-6 (R&D Systems), anti-IL-6 receptor and isotype (IgG2b) control antibodies (Biolegend, San Diego, CA, USA), ... Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2
In Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2002
... of growth factors: 10pg/ml GM-CSF, 10pg/ml G-CSF, 10ng/ml SCF, 10ng/ml LIF, 10ng/ml MIP-1α, 0.2 ng/ml IL-6 (PeproTech Inc., Rocky Hill, NJ, USA, and StemCell Technologies).