Oxyresveratrol suppresses lipopolysaccharide-induced inflammatory responses in murine macrophages.
Pusan, South Korea. In Hum Exp Toxicol, 25 Dec 2014
Production of nitric oxide (NO), prostaglandin E2 (PGE2), messenger RNA (mRNA) and protein expressions of inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), interleukin 6 (IL-6), and granulocyte macrophage colony-stimulating factor (GM-CSF), phosphorylation of mitogen-activated protein kinases (MAPKs; extracellular signal-regulated kinase (ERK), c-Jun N-terminal kinase (JNK), p38), and the activation of nuclear factor κ-light chain enhancer of activated B cells (NFκB) with OxyR were assayed in LPS-stimulated RAW264.7 cells.
Metallic debris from metal-on-metal total hip arthroplasty regulates periprosthetic tissues.
Magdeburg, Germany. In World J Orthop, 18 Dec 2014
We propose that periprosthetic tissue reactions be thought of as (1) gross (metallosis, necrosis, cyst formation and pseudotumour); (2) histological (macrophage-dominated, lymphocyte-dominated or mixed); and (3) molecular (expression of inflammatory mediators and cytokines such as interleukin-6 and tumor necrosis factor-alpha).
Helicobacter pylori and neurological diseases: Married by the laws of inflammation.
Mexico. In World J Gastrointest Pathophysiol, 15 Dec 2014
Infection with H. pylori usually persists throughout life, resulting in a chronic inflammatory response with local secretion of numerous inflammatory mediators including chemokines [interleukin (IL)-8, macrophage chemotactic protein (MCP)-1, growth-regulated oncogene (GRO)-α] and cytokines [IL-1β, tumor necrosis factor (TNF)-α, IL-6, IL-12, interferon (IFN)-γ], which can pass into the circulation and have a systemic effect.
Evidence and Mechanisms of Fat Depletion in Cancer.
Edmonton, Canada. In Nutrients, Dec 2013
Inflammatory cytokines such as interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α), and interleukin-1 beta (IL-1β) produced by the tumor or adipose tissue may also contribute to adipose depletion.
Context-specific roles for paracrine IL-6 in lymphomagenesis.
More papers using
Cambridge, United States. In Genes Dev, 2012
It was shown that paracrine IL-6 signaling promoted the survival of transplanted hematopoietic stem cells, while also initiating a secretory program in the bone marrow that inhibits the development of B-cell malignancies.
Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10–a role for IL-1 beta?
In Journal of Neuroinflammation, 2003
... Systems, Abingdon, UK), IL-6 and non-target (NT) siRNA (Invitrogen, Paisley, UK), recombinant IL-6 (R&D Systems), anti-IL-6 receptor and isotype (IgG2b) control antibodies (Biolegend, San Diego, CA, USA), ... Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2
In Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 2002
... of growth factors: 10pg/ml GM-CSF, 10pg/ml G-CSF, 10ng/ml SCF, 10ng/ml LIF, 10ng/ml MIP-1α, 0.2 ng/ml IL-6 (PeproTech Inc., Rocky Hill, NJ, USA, and StemCell Technologies).