Adaptive Response in Mammalian Cells Exposed to Non-Ionizing Radiofrequency Fields: A Review and Gaps in knowledge.
San Antonio, United States. In Mutat Res, 15 Mar 2014
In in vivo studies, exposure of rodents to radiofrequency fields and then to lethal/sub-lethal doses of γ-radiation showed survival advantage, significantly decreased damage in hematopoietic tissues, decreased genetic damage in blood leukocytes and bone marrow cells, increased numbers of colony forming units in bone marrow, increased levels of colony stimulating factor and interleukin-3 in the serum and increased expression of genes related to cell cycle.
Signalling by the βc family of cytokines.
Adelaide, Australia. In Cytokine Growth Factor Rev, Jun 2013
The GM-CSF, IL-3 and IL-5 family of cytokines, also known as the βc family due to their receptors sharing the signalling subunit βc, regulates multiple biological processes such as native and adaptive immunity, inflammation, normal and malignant hemopoieis, and autoimmunity.
The pharmacological modulation of allergen-induced asthma.
Hamilton, Canada. In Inflammopharmacology, Apr 2013
Examples are TPI ASM8, an inhaled anti-sense oligonucleotide drug product, which attenuated both early and LARs via inhibition of the target gene mRNA of chemokine receptor 3, and the common β chain of interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor receptor.
Association of matrix metalloproteinase 8 genetic polymorphisms with bronchial asthma in a Japanese population.
Kurashiki, Japan. In Allergy Rhinol (providence), 2012
We investigated whether 31 single nucleotide polymorphisms (SNPs) in genes encoding cytokines or monokines (interleukin [IL]-5R, matrix metalloproteinase [MMP] 8, beta2 adrenergic receptor, cytotoxic T-lymphocyte-associated antigen 4, IL-3, C-reactive protein, cytochrome P450 (CYP) 2C9, CYP3A4, a disintegrin and metalloproteinase [ADAM] 33, cysteinyl leukotriene receptor [CysLTR] 1, CysLTR2, eosinophilic cationic protein, glucocorticoid receptor, and leukotriene A 4 hydrolase) are related to asthma development in 206 Japanese bronchial asthma patients and 127 healthy controls.
[Morphogenesis, structure and properties of lymphatic vessels].
Warsaw, Poland. In Postepy Hig Med Dosw (online), 2011
Mechanisms of lymphatic vessel formation during embryonic development and in pathological conditions, such as tumorigenesis, wound healing, and metastasis, is regulated by a plethora of growth factors and molecules, among which the most important are VEGF-C, VEGF-D, HGF, FGF, retinoic acid, IL-3, and IL-7.