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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

Interferon, beta 1, fibroblast

Interferon-beta, IFN-beta
suppresses the growth of rat glioma cells [RGD, Feb 2006] (from NCBI)
Top mentioned proteins: CAN, HAD, Interferon Regulatory Factor-3, NF-kappaB, IFN-gamma
Papers using Interferon-beta antibodies
Derivation of the SLEDAI. A disease activity index for lupus patients. The Committee on Prognosis Studies in SLE
Jin Dong-Yan, In PLoS ONE, 1991
... Human IFN-beta expression plasmid was purchased from OriGene (SC127861) ...
Papers on Interferon-beta
Identification of Th1/Th2 regulatory switch to promote healing response during leishmaniasis: a computational approach.
Sarkar et al., Pune, India. In Eurasip J Bioinform Syst Biol, Dec 2015
Through our study, we also observe that Leishmania infection may induce an upregulation of IFN-beta production from the APC that may lead to an upregulation of the RAP1 and SOCS3 proteins inside the T cell, the potential inhibitors of MAPK and JAK-STAT signaling pathways, respectively, via the TYK2-mediated pathway.
Comparative Neuroregenerative Effects of C-Phycocyanin and IFN-Beta in a Model of Multiple Sclerosis in Mice.
Pentón-Arias et al., Havana, Cuba. In J Neuroimmune Pharmacol, Dec 2015
C-Pc (2, 4 or 8 mg/kg i.p.) or IFN-beta (2000 IU, s.c.) was administered daily once a day or every other day, respectively, starting at disease onset, which differ among EAE mice between 11 and 15 days postinduction.
Respiratory Syncytial Virus Persistence in Murine Macrophages Impairs IFN-β Response but Not Synthesis.
Gómez et al., Mexico. In Viruses, Oct 2015
In this model, interferon regulatory factor 3 was constitutively active and located at nuclei of persistently infected cells, inducing expression of IFN-beta mRNA and protein.
Interferon-Beta, a Decisive Factor in Angiogenesis and Arteriogenesis.
van der Pouw Kraan et al., Amsterdam, Netherlands. In J Interferon Cytokine Res, Jun 2015
In this review we discuss the current literature on the effects of type I interferons (IFN) and their downstream effectors on vascular growth in experimental models in vitro and in vivo.
Natalizumab in the pediatric MS population: results of the Italian registry.
MS Study Group-Italian Society of Neurology et al., Gallarate, Italy. In Bmc Neurol, 2014
BACKGROUND: Natalizumab is a promising option for pediatric multiple sclerosis (MS) patients with active evolution and a poor response to Interferon-beta or Glatiramer Acetate.
Systematic Review: Impact of Interferon-based Therapy on HCV-related Hepatocellular Carcinoma.
Kao et al., Taipei, Taiwan. In Sci Rep, 2014
We identified 6 trials evaluated the effectiveness of interferon (IFN)-alfa treatment, 3 studies examined pegylated interferon-alfa treatment, and 2 studies examined IFN-beta treatment.
Host Innate Immune Responses of Ducks Infected with Newcastle Disease Viruses of Different Pathogenicities.
Ren et al., Guangzhou, China. In Front Microbiol, 2014
Real-time quantitative polymerase chain reaction showed that the expression of TLR3, TLR7, RIG-I, MDA5, IL-1β, IL-2, IL-6, IL-8, IFN-alpha, IFN-beta, IFN-gamma in the lungs was significantly greater than in the respective thymus genes during the early post infection stage.
Biomarkers of interferon Beta therapy in multiple sclerosis.
Dhib-Jalbut et al., New York City, United States. In J Interferon Cytokine Res, 2014
Interferon-beta (IFNβ) has been a mainstay of MS treatment for more than 20 years after being proven to reduce relapse frequency and development of new lesions on magnetic resonance imaging.
[Recent progress in interferon induced protein GBP1 research].
Zheng et al., In Bing Du Xue Bao, 2014
Recent studies have proved that IFN-alpha, IFN-beta, IFN-gamma, IL1alpha, IL1beta, TNF-alpha and LPS can induce GBP1 expression; hence, the diverse biological functions of GBP1 have been gradually deduced and exploited.
Interferons-beta versus glatiramer acetate for relapsing-remitting multiple sclerosis.
Vaona et al., Milano, Italy. In Cochrane Database Syst Rev, 2013
The IFNs analysed in comparison with GA were IFN-beta 1b 250 mcg (two trials, 933 participants), IFN-beta 1a 44 mcg (two trials, 441 participants) and IFN-beta 1a 30 mcg (two trials, 305 participants).
USP18 establishes the transcriptional and anti-proliferative interferon α/β differential.
Pellegrini et al., Paris, France. In Biochem J, 2012
IFNbeta induces Stat (signal transducer and activator of transcription) phosphorylation and transcriptional activation of ISGs (interferon-stimulated genes)
IFN-β expression is directly activated in human neutrophils transfected with plasmid DNA and is further increased via TLR-4-mediated signaling.
Cassatella et al., Verona, Italy. In J Immunol, 2012
Infection of neutrophils with intracellular pathogens, such as Bartonella henselae, Listeria monocytogenes, Legionella pneumophila, or adenovirus type 5, promote a marked induction of IFN-beta mRNA expression.
Human bocavirus NP1 inhibits IFN-β production by blocking association of IFN regulatory factor 3 with IFNB promoter.
Wang et al., Wuhan, China. In J Immunol, 2012
Bocavirus nonstructural protein (NP)1 suppresses human IFN-beta production by targeting the IFN regulatory factor (IRF)-3-signaling pathway.
Regulatory dendritic cells program B cells to differentiate into CD19hiFcγIIbhi regulatory B cells through IFN-β and CD40L.
Cao et al., Shanghai, China. In Blood, 2012
We found that regulatory dendritic cell-derived IFN-beta and CD40 ligand are responsible for the differentiation of CD19(hi)FcgammaIIb(hi) B cells.
Exploiting synthetic lethality for the therapy of ABC diffuse large B cell lymphoma.
Staudt et al., Bethesda, United States. In Cancer Cell, 2012
Data show that in a cereblon-dependent fashion, lenalidomide downregulates IRF4 and SPIB, transcription factors that together prevent IFNbeta production.
The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3.
Seed et al., Boston, United States. In Nat Immunol, 2010
Viral infection induces type I interferons (IFN-alpha and IFN-beta) that recruit unexposed cells in a self-amplifying response.
The cytosolic nucleic acid sensor LRRFIP1 mediates the production of type I interferon via a beta-catenin-dependent pathway.
Cao et al., Shanghai, China. In Nat Immunol, 2010
Here we show that the cytosolic nucleic acid-binding protein LRRFIP1 contributed to the production of interferon-beta (IFN-beta) induced by vesicular stomatitis virus (VSV) and Listeria monocytogenes in macrophages.
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis.
Raman et al., Stanford, United States. In Nat Med, 2010
Interferon-beta (IFN-beta) is the major treatment for multiple sclerosis.
Activation of innate immune antiviral responses by Nod2.
Bose et al., San Antonio, United States. In Nat Immunol, 2009
Here we show that nucleotide-binding oligomerization domain 2 (Nod2) can also function as a cytoplasmic viral PRR by triggering activation of interferon-regulatory factor 3 (IRF3) and production of interferon-beta (IFN-beta).
DNA makes RNA makes innate immunity.
O'Neill, Dublin, Ireland. In Cell, 2009
Microbial DNA in the cytosol induces production of interferon-beta (IFN-beta) and an innate immune response.
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