Host Innate Immune Responses of Ducks Infected with Newcastle Disease Viruses of Different Pathogenicities.
Guangzhou, China. In Front Microbiol, 2014
Real-time quantitative polymerase chain reaction showed that the expression of TLR3, TLR7, RIG-I, MDA5, IL-1β, IL-2, IL-6, IL-8, IFN-alpha, IFN-beta, IFN-gamma in the lungs was significantly greater than in the respective thymus genes during the early post infection stage.
Biomarkers of interferon Beta therapy in multiple sclerosis.
New York City, United States. In J Interferon Cytokine Res, 2014
Interferon-beta (IFNβ) has been a mainstay of MS treatment for more than 20 years after being proven to reduce relapse frequency and development of new lesions on magnetic resonance imaging.
Activation of innate immune antiviral responses by Nod2.
San Antonio, United States. In Nat Immunol, 2009
Here we show that nucleotide-binding oligomerization domain 2 (Nod2) can also function as a cytoplasmic viral PRR by triggering activation of interferon-regulatory factor 3 (IRF3) and production of interferon-beta (IFN-beta).