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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

ITGB5 integrin, beta 5

integrin beta5
Top mentioned proteins: fibronectin, vitronectin, HAD, CD44, Actin
Papers on integrin beta5
p21-activated kinase 4 phosphorylation of integrin beta5 Ser-759 and Ser-762 regulates cell migration.
Strömblad et al., Huddinge, Sweden. In J Biol Chem, 2010
We here identified a unique PAK4-binding membrane-proximal integrin beta5-SERS-motif involved in controlling cell attachment and migration.
Human cleft lip and palate fibroblasts and normal nicotine-treated fibroblasts show altered in vitro expressions of genes related to molecular signaling pathways and extracellular matrix metabolism.
Bodo et al., Perugia, Italy. In J Cell Physiol, 2010
Among the ECM genes, fibronectin, syndecan, integrin alpha2, and MMP13 genes were concordantly modulated, while integrin beta5, and decorin genes were discordantly modulated.
Regulation of cell proliferation and migration by TAK1 via transcriptional control of von Hippel-Lindau tumor suppressor.
Tan et al., Singapore, Singapore. In J Biol Chem, 2009
We show here that, for wound healing, transforming growth factor-beta-activated kinase 1 (TAK1) in keratinocytes activates von Hippel-Lindau tumor suppressor expression, which in turn represses the expression of platelet-derived growth factor-B (PDGF-B), integrin beta1, and integrin beta5 via inhibition of the Sp1-mediated signaling pathway in the keratinocytes.
Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability.
GeneRIF
Pittet et al., San Francisco, United States. In Am J Respir Cell Mol Biol, 2009
These results demonstrate the critical role of the RhoA/alphavbeta5 integrin pathway in mediating Pseudomonas aeruginosa-induced lung vascular permeability.
The Foxc2 transcription factor regulates angiogenesis via induction of integrin beta3 expression.
Kume et al., Nashville, United States. In J Biol Chem, 2008
Here, through gene expression profiling in endothelial cells, we identified molecules associated with cell-extracellular matrix interactions, integrin beta3 (Itgb3), integrin beta5 (Itgb5), and fibronectin, as downstream targets of Foxc2.
Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function.
Pittet et al., San Francisco, United States. In Am J Respir Cell Mol Biol, 2007
Knockout mice homozygous for a null mutation of the integrin beta5 subunit were also protected from lung vascular permeability in VILI.
Extracellular matrix-mediated tissue remodeling following axial movement of teeth.
Diekwisch et al., Chicago, United States. In J Histochem Cytochem, 2007
Microarray analysis and semiquantitative RT-PCR demonstrated a significant increase in collagen I, integrin beta5, and SPARC gene expression as revealed by comparison between the unopposed molar group and the control group.
[Analysis of genes related to sensitivity to navalbine and docetaxel in 10 lung cancer cell lines].
Sui et al., Harbin, China. In Zhonghua Zhong Liu Za Zhi, 2006
(4) Rab 1, Rab 3, Rho B, Rho C, Rac 1, Rac 2, Gho GDI beta, CD44, integrin alpha5, integrin alpha6, integrin beta5, vinculin showed to be cytoskeleton-related genes differently expressing in SCLC or NSCLC cell lines.
Four and half lim protein 2 (FHL2) stimulates osteoblast differentiation.
Cheng et al., Saint Louis, United States. In J Bone Miner Res, 2006
MATERIALS AND METHODS: Yeast two hybrid assay was used to identify proteins interacting with the cytoplasmic domain of integrin beta5 subunit.
Antimetastatic effect of salvicine on human breast cancer MDA-MB-435 orthotopic xenograft is closely related to Rho-dependent pathway.
Ding et al., Shanghai, China. In Clin Cancer Res, 2005
A comparison of gene expression profiles of primary tumors and lung metastatic focus between salvicine-treated and untreated groups using the CLOTECH Atlas human Cancer 1.2 cDNA microarray revealed that genes involved in tumor metastasis, particularly those closely related to cell adhesion and motility, were obviously down-regulated, including fibronectin, integrin alpha3, integrin beta3, integrin beta5, FAK, paxillin, and RhoC.
Differential modulation of integrin expression in chondrocytes during expansion for tissue engineering.
Riedel et al., Mannheim, Germany. In In Vivo, 2005
The components of the vitronectin-receptor, integrin alpha2b, alpha v, as well as integrin beta5, were activated on day 21, but neither vitronectin nor osteopontin were expressed by the cells.
Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state.
Teitelbaum et al., San Francisco, United States. In J Bone Miner Res, 2005
UNLABELLED: Integrin alphavbeta5 is expressed on osteoclast precursors and is capable of recognizing the same amino acid motif as alphavbeta3.
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line.
Moses et al., Nashville, United States. In Breast Cancer Res, 2002
Cell cycle pathway examination demonstrated downregulation of cyclin D2, c-myc, Id2, p107, E2F5, cyclin A, cyclin B, and cyclin H. Examination of cell adhesion-related genes revealed upregulation of c-Jun, alpha-actinin, actin, myosin light chain, p120cas catenin (Catns), alpha-integrin, integrin beta5, fibronectin, IQGAP1, and mCalpain.
Src-mediated coupling of focal adhesion kinase to integrin alpha(v)beta5 in vascular endothelial growth factor signaling.
Cheresh et al., Los Angeles, United States. In J Cell Biol, 2002
Supporting these results, mice deficient in either pp60c-src or integrin beta5, but not integrin beta3, have a reduced VP response to VEGF.
An RGDS peptide-binding receptor, FR-1R, localizes to the basal side of the ectoderm and to primary mesenchyme cells in sand dollar embryos.
Sofuku et al., Aomori, Japan. In Dev Growth Differ, 2001
FR-1R was weakly recognized by antihuman integrin beta5 subunit pAb.
AlphaVbeta5 integrin: a co-receptor for adeno-associated virus type 2 infection.
Impact
Samulski et al., Chapel Hill, United States. In Nat Med, 1999
Viral overlay experiments on purified plasma membrane proteins as well as immunoprecipitated integrin beta5 subunit demonstrated that AAV directly associates with the beta5 subunit of alphaVbeta5 integrin.
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