Bile acid receptors and nonalcoholic fatty liver disease.
Los Angeles, United States. In World J Hepatol, Jan 2016
Insulin resistance and derangement of lipid metabolism, accompanied by activation of the pro-inflammatory response and fibrogenesis, are essential pathways in the development of the more clinically significant form of NAFLD, known as nonalcoholic steatohepatitis (NASH).
HDL and glucose metabolism: current evidence and therapeutic potential.
Melbourne, Australia. In Front Pharmacol, 2014
HDL may mediate effects on glucose metabolism through actions in multiple organs (e.g., pancreas, skeletal muscle, heart, adipose, liver, brain) by three distinct mechanisms: (i) Insulin secretion from pancreatic beta cells, (ii) Insulin-independent glucose uptake, (iii) Insulin sensitivity.