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GoPubMed Proteins lists recent and important papers and reviews for proteins. Page last changed on 19 Aug 2016.

PHD finger protein 5A

This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes. [provided by RefSeq, Jul 2008] (from NCBI)
Top mentioned proteins: HAD, CAN, ACID, INI1, V1a
Papers on INI
Deep analysis of HIV-1 natural variability across HIV-1 variants at residues associated with integrase inhibitor (INI) resistance in INI-naive individuals.
Holguín et al., Madrid, Spain. In J Antimicrob Chemother, Feb 2016
METHODS: We evaluated the frequency of major, secondary and rare amino acid changes associated with INI resistance (INI-R) in 6706 sequences from 3791 INI-naive individuals carrying a large panel of different HIV-1 variants retrieved from GenBank, including four groups: M (6663), O (24), N (15) and P (4).
Dietary administration of a commercial mixed-species probiotic improves growth performance and modulates the intestinal immunity of tilapia, Oreochromis niloticus.
Merrifield et al., Newport, United Kingdom. In Fish Shellfish Immunol, Jan 2016
3g kg(-1) probiotic (PRO-3), pulsed probiotic feeding (PRO-PULSE) or an initial probiotic feed followed by control feeding (PRO-INI).
Atypical Teratoid Rhabdoid Tumor in a Teenager with Unusual Infiltration Into the Jugular Foramen.
Crawford et al., San Diego, United States. In World Neurosurg, Dec 2015
Immunohistochemistry plays an important role in establishing the diagnosis with a loss of INI-1 staining in tumor cells.
Lumbar spinal atypical teratoid rhabdoid tumor.
Wolff et al., Cleveland, United States. In J Clin Neurosci, Dec 2015
The tumor cells stained with antibodies to synaptophysin and CAM5.2, and showed no immunoreactivity to INI-1 antibody.
Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades.
CORONET Study Group et al., Roma, Italy. In J Antimicrob Chemother, Nov 2015
OBJECTIVES: The aim of this study was to characterize the prevalence and patterns of genotypic integrase inhibitor (INI) resistance in relation to HIV-1 clade.
Development of the 5-HT2CR-Tango System Combined with an EGFP Reporter Gene.
Tanaka et al., Kyoto, Japan. In J Mol Neurosci, Oct 2015
For validation of our system, we measured activity of two 5-HT2CR RNA-editing isoforms (INI and VGV) in HEK293 cells transfected with EGFP reporter gene.
Probing the Biomimetic Ice Nucleation Inhibition Activity of Poly(vinyl alcohol) and Comparison to Synthetic and Biological Polymers.
Gibson et al., Coventry, United Kingdom. In Biomacromolecules, Oct 2015
Here well-defined poly(vinyl alcohol), synthesized by RAFT/MADIX polymerization, is investigated for its ice nucleation inhibition (INI) activity, in contrast to its established ice growth inhibitory properties and compared to other synthetic polymers.
Atypical teratoid/ rhabdoid tumor, an immunohistochemical study of potential diagnostic and prognostic markers.
Amayiri et al., Amman, Jordan. In Neuropathology, Aug 2015
Despite the heterogeneous morphology and/or immunoprofile, its diagnosis nowadays relies on the negative INI-1/BAF47 nuclear immunostain in tumor cells.
Is Insulin Action in the Brain Relevant in Regulating Blood Glucose in Humans?
Lewis et al., Toronto, Canada. In J Clin Endocrinol Metab, Jul 2015
METHODS AND RESULTS: Intransal insulin (INI) administration increases CNS insulin concentration.
Pharmacokinetic and pharmacodynamic drug interactions between antiretrovirals and oral contraceptives.
Nwokolo et al., London, United Kingdom. In Clin Pharmacokinet, 2015
However, the INI elvitegravir, which is given in combination with cobicistat, requires a dose of estrogen of at least 30 µg.
Cost-Effectiveness of Dolutegravir in HIV-1 Treatment-Experienced (TE) Patients in France.
Aubin et al., Paris, France. In Plos One, 2014
OBJECTIVES: To evaluate the cost-effectiveness of a new generation integrase inhibitor (INI), dolutegravir (DTG), in France, in treatment-experienced (TE) and INI-naïve HIV-infected adults with at least two classes resistance compared to raltegravir (RAL), by adapting previously published Anti-Retroviral Analysis by Monte Carlo Individual Simulation (ARAMIS) model.
Pseudomyogenic hemangioendothelioma/epithelioid sarcoma-like hemangioendothelioma of the lower limb: report of a rare case.
Wang et al., Shenyang, China. In Diagn Pathol, 2014
The tumor cells show diffuse strong expression of Factor VIII, Fli-1, INI-1, vimentin, MDM2, and CDK4, local expression of CD31, AE1/AE3, EMA and P63, and no expression of CD34, S-100, actin-sm, desmin, MyoD1, and HMB45.
Proximal-type epithelioid sarcoma of the vulva with INI1 diagnostic utility.
Ro et al., Seoul, South Korea. In Ann Diagn Pathol, 2012
Reported herein is the diagnostic utility of INI-1 on PES and the possible relationship between PES and malignant rhabdoid tumor of the soft tissue, besides a collective review of the reported cases of PES of the vulva and of the current case.
High-grade carcinomas involving the renal sinus: report of a case and review of the differential diagnosis and immunohistochemical expression.
Kunju et al., Ann Arbor, United States. In Arch Pathol Lab Med, 2012
Renal medullary carcinoma is characterized by an appropriate clinical setting and consistent loss of nuclear expression of integrase interactor 1 (INI-1).
Dolutegravir for the treatment of HIV.
Murphy et al., Paris, France. In Expert Opin Investig Drugs, 2012
Integrase inhibitors (INI) are a new class of antiretroviral drugs that block the action of HIV integrase, which catalyses several key steps in the virus life cycle which are essential for insertion of the viral genome into the DNA of host cell.
Ini, a small nuclear protein that enhances the response of the connexin43 gene to estrogen.
Werner et al., Miami, United States. In Endocrinology, 2003
that Ini's physiological role in myometrium is to modulate the response of the cx43 gene to estrogen.
Identification and characterization of a novel murine multigene family containing a PHD-finger-like motif.
Engel et al., Göttingen, Germany. In Biochem Biophys Res Commun, 2002
The molecular and genetic research in this paper is performed on mouse but the paper identifies and discusses homologues found in human genomic sequence databases.
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