Adverse effects of glucocorticoids: coagulopathy.
Rio de Janeiro, Brazil. In Eur J Endocrinol, Oct 2015
Most studies have demonstrated that this hypercoagulable state is explained by increased levels of procoagulant factors, mainly factors VIII, IX, and von Willebrand factor, and also by an impaired fibrinolytic capacity, which mainly results from an elevation in plasminogen activator inhibitor 1.
Noncoding RNAs, cytokines, and inflammation-related diseases.
Viçosa, Brazil. In Faseb J, Sep 2015
In this context, this review summarizes findings in the field, highlighting those noncoding RNAs that regulate inflammation, with emphasis on recognized mediators such as TNF-α, IL-1, IL-6, IL-18, intercellular adhesion molecule 1, VCAM-1, and plasminogen activator inhibitor 1.
Madagascar. In Unknown Journal, Jun 2015
Hyperuricemia, microvascular angina and elevated plasminogen activator inhibitor 1 (PAI-1) were later proposed as possible additional components of the same syndrome (1,2).