Jack of all trades: thymosin α1 and its pleiotropy.
Perugia, Italy. In Ann N Y Acad Sci, Oct 2012
Additionally, the ability of Tα1 to activate the indoleamine 2,3-dioxygenase enzyme-which confers immune tolerance during transplantation and restrains the vicious circle of chronic inflammation-has been a turning point, suggesting a potential, specific function in immunity.
Highlights of 10 years of immunology in Nature Reviews Immunology.
New Haven, United States. In Nat Rev Immunol, 2011
Highlights include our improved understanding of Toll-like receptor signalling, and of immune regulation mediated by regulatory T cells, indoleamine 2,3-dioxygenase, myeloid-derived suppressor cells and interleukin-10.