An in silico approach for understanding the molecular evolution of clinically important metallo-beta-lactamases.
Calcutta, India. In Infect Genet Evol, 2013
Based on sequence diversity and selection pressure, IMP-1, IMP-8, IMP-9, IMP-21, IMP-27, IMP-20 and IMP-26 among IMP genes; VIM-1, VIM-2, VIM-13, VIM-29, VIM-18 and VIM-7 among VIM genes and NDM-1 had been selected for in silico analysis.
Role of Extrachromosomal Histone H2B on Recognition of DNA Viruses and Cell Damage.
Ibaraki, Japan. In Front Genet, 2012
It also physically interacts with interferon (IFN)-β promoter stimulator 1 (IPS-1), an essential adaptor molecule that activates innate immunity, through COOH-terminal importin 9-related adaptor organizing histone H2B and IPS-1 (CIAO), resulting in a distinct signaling complex that induces dsDNA-induced type I IFN production.